Inflammatory signalling in atrial cardiomyocytes: a novel unifying principle in atrial fibrillation pathophysiology

D Dobrev, J Heijman, R Hiram, N Li… - Nature Reviews …, 2023 - nature.com
Inflammation has been implicated in atrial fibrillation (AF), a very common and clinically
significant cardiac rhythm disturbance, but its precise role remains poorly understood. Work …

Molecular basis of atrial fibrillation pathophysiology and therapy: a translational perspective

S Nattel, J Heijman, L Zhou, D Dobrev - Circulation research, 2020 - Am Heart Assoc
Atrial fibrillation (AF) is a highly prevalent arrhythmia, with substantial associated morbidity
and mortality. There have been significant management advances over the past 2 decades …

2023 ACC/AHA/ACCP/HRS guideline for the diagnosis and management of atrial fibrillation: a report of the American College of Cardiology/American Heart …

Writing Committee Members, JA Joglar… - Journal of the American …, 2024 - jacc.org
Abstract Aim The “2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management
of Patients With Atrial Fibrillation” provides recommendations to guide clinicians in the …

Modulation of Cardiac Arrhythmogenesis by Epicardial Adipose Tissue: JACC State-of-the-Art Review

AC Ernault, VMF Meijborg, R Coronel - Journal of the American College of …, 2021 - jacc.org
Obesity is a significant risk factor for arrhythmic cardiovascular death. Interactions between
epicardial adipose tissue (EAT) and myocytes are thought to play a key role in the …

Obesity and atrial fibrillation: a narrative review from arrhythmogenic mechanisms to clinical significance

H Shu, J Cheng, N Li, Z Zhang, J Nie, Y Peng… - Cardiovascular …, 2023 - Springer
The prevalence of obesity and atrial fibrillation (AF), which are inextricably linked, is rapidly
increasing worldwide. Obesity rates are higher among patients with AF than healthy …

Role of inflammation in the pathogenesis of atrial fibrillation

K Ihara, T Sasano - Frontiers in Physiology, 2022 - frontiersin.org
Atrial fibrillation (AF) is one of the most common arrhythmias encountered in clinical practice.
AF is a major risk factor for stroke, which is associated with high mortality and great disability …

Fir (e) ing the rhythm: inflammatory cytokines and cardiac arrhythmias

PE Lazzerini, A Abbate, M Boutjdir… - Basic to Translational …, 2023 - jacc.org
Inflammatory activation is increasingly recognized as a nonconventional risk factor for
arrhythmias, and experimental studies provided robust evidence that this association is …

Electroimmunology and cardiac arrhythmia

J Grune, M Yamazoe, M Nahrendorf - Nature reviews cardiology, 2021 - nature.com
Conduction disorders and arrhythmias remain difficult to treat and are increasingly prevalent
owing to the increasing age and body mass of the general population, because both are risk …

Cardiac arrhythmias in patients with COVID‐19

Y Wang, Z Wang, G Tse, L Zhang, EY Wan… - Journal of …, 2020 - Wiley Online Library
The emergence of coronavirus disease 2019 (COVID‐19), caused by the severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has become a major global public …

Immune remodeling and atrial fibrillation

Y Yao, M Yang, D Liu, Q Zhao - Frontiers in Physiology, 2022 - frontiersin.org
Atrial fibrillation (AF) is a highly prevalent arrhythmia that causes high morbidity and
mortality. However, the underlying mechanism of AF has not been fully elucidated. Recent …