Negative regulation of inflammation by SIRT1

J Xie, X Zhang, L Zhang - Pharmacological Research, 2013 - Elsevier
Sirtuin 1 (SIRT1), the mammalian Sir2 homologue, is a class III histone deacetylase shown
to act on a wide range of histones and non-histone substrates. Numerous studies have …

Human lipopolysaccharide models provide mechanistic and therapeutic insights into systemic and pulmonary inflammation

D Brooks, LC Barr, S Wiscombe… - European …, 2020 - Eur Respiratory Soc
Inflammation is a key feature in the pathogenesis of sepsis and acute respiratory distress
syndrome (ARDS). Sepsis and ARDS continue to be associated with high mortality. A key …

Exposure to dust mite allergen and endotoxin in early life and asthma and atopy in childhood

JC Celedón, DK Milton, CD Ramsey… - Journal of allergy and …, 2007 - Elsevier
BACKGROUND: There has been no longitudinal study of the relation between concurrent
exposure to dust mite allergen and endotoxin in early life and asthma and atopy at school …

Cyanobacteria, cyanotoxins and lipopolysaccharides in aerosols from inland freshwater bodies and their effects on human bronchial cells

P Labohá, E Sychrová, O Brózman… - Environmental …, 2023 - Elsevier
Components of cyanobacterial water blooms were quantified in aerosols above agitated
water surfaces of five freshwater bodies. The thoracic and respirable aerosol fraction (0.1 …

Pediatric respiratory and systemic effects of chronic air pollution exposure: nose, lung, heart, and brain pathology

L Calderón-Garcidueñas, M Franco-Lira… - Toxicologic …, 2007 - journals.sagepub.com
Exposures to particulate matter and gaseous air pollutants have been associated with
respiratory tract inflammation, disruption of the nasal respiratory and olfactory barriers …

LPS-induced inflammatory response is suppressed by Wnt inhibitors, Dickkopf-1 and LGK974

J Jang, Y Jung, Y Kim, E Jho, Y Yoon - Scientific reports, 2017 - nature.com
In this study, LPS-induced inflammatory responses in BEAS-2B human bronchial epithelial
cells and human umbilical vein endothelial cell (HUVEC) s were found to be prevented by …

Berberine suppresses inflammatory agents-induced interleukin-1β and tumor necrosis factor-α productions via the inhibition of IκB degradation in human lung cells

CH Lee, JC Chen, CY Hsiang, SL Wu, HC Wu… - Pharmacological …, 2007 - Elsevier
Pulmonary inflammation is a characteristic of many lung diseases. Increased levels of pro-
inflammatory cytokines, such as interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) …

Occurrence of antibiotic-resistant bacteria and endotoxin associated with the land application of biosolids

JP Brooks, SL Maxwell, C Rensing… - Canadian Journal of …, 2007 - cdnsciencepub.com
The purpose of this study was to determine the prevalence of antibiotic-resistant bacteria
and endotoxin in soil after land application of biosolids. Soil was collected over a 15 month …

Endotoxin and occupational airway disease

R Rylander - Current opinion in allergy and clinical immunology, 2006 - journals.lww.com
Endotoxin, as well as other agents derived from microbes, are important causative agents for
occupational respiratory and other diseases, and exposure may occur in a large variety of …

Endotoxin Tolerance Creates Favourable Conditions for Cancer Development

K Roy, HM Kozłowski, T Jędrzejewski, J Sobocińska… - Cancers, 2023 - mdpi.com
Simple Summary Macrophages, depending on their phenotype, can either destroy or
stimulate cancer cells. Therefore, it is very important to identify the conditions under which …