[HTML][HTML] Lipid emulsion for treating local anesthetic systemic toxicity

SH Ok, JM Hong, SH Lee, JT Sohn - International journal of …, 2018 - ncbi.nlm.nih.gov
Lipid emulsion has been shown to be an effective treatment for systemic toxicity induced by
local anesthetics, which is reflected in case reports. A systemic review and meta-analysis …

[HTML][HTML] Lipid emulsion to treat acute poisonings: mechanisms of action, indications, and controversies

K Jaffal, L Chevillard, B Mégarbane - Pharmaceutics, 2023 - mdpi.com
Biodetoxification using intravenous lipid emulsion (ILE) in acute poisoning is of growing
interest. As well as for local anesthetics, ILE is currently used to reverse toxicity caused by a …

[HTML][HTML] Intravenous lipid emulsion for the treatment of poisonings in 313 dogs and 100 cats (2016–2020)

C Markert, RM Heilmann, D Kiwitz… - Frontiers in veterinary …, 2023 - frontiersin.org
Introduction The aim of this retrospective study was to analyze the effect and potential
adverse effects of intravenous lipid emulsion (ILE) in poisoned dogs and cats over a 5 years …

The emerging threat of superwarfarins: history, detection, mechanisms, and countermeasures

DL Feinstein, BS Akpa, MA Ayee… - Annals of the New …, 2016 - Wiley Online Library
Superwarfarins were developed following the emergence of warfarin resistance in rodents.
Compared to warfarin, superwarfarins have much longer half‐lives and stronger affinity to …

Nanotherapeutics for Alleviating Anesthesia‐Associated Complications

B Lu, L Wei, G Shi, J Du - Advanced Science, 2024 - Wiley Online Library
Current management of anesthesia‐associated complications falls short in terms of both
efficacy and safety. Nanomaterials with versatile properties and unique nano‐bio …

[HTML][HTML] Advances of nano-structured extended-release local anesthetics

Y He, L Qin, Y Huang, C Ma - Nanoscale Research Letters, 2020 - Springer
Extended-release local anesthetics (LAs) have drawn increasing attention with their
promising role in improving analgesia and reducing adverse events of LAs. Nano-structured …

Lipid emulsion improves survival in animal models of local anesthetic toxicity: a meta-analysis

MR Fettiplace, DJ McCabe - Clinical Toxicology, 2017 - Taylor & Francis
Abstract Introduction: The Lipid Emulsion Therapy workgroup, organized by the American
Academy of Clinical Toxicology, recently conducted a systematic review, which subjectively …

Venlafaxine Intoxication with Development of Takotsubo Cardiomyopathy: Successful Use of Extracorporeal Life Support, Intravenous Lipid Emulsion and Cytosorb®

I Schroeder, M Zoller, M Angstwurm… - … Journal of Artificial …, 2017 - journals.sagepub.com
We describe a young patient who ingested 18 g (240 times the daily therapeutic dose) of
venlafaxine in a suicide attempt. She developed severe cardiomyopathy in a takotsubo …

Lipid therapy for intoxications

JH Robben, MA Dijkman - Veterinary Clinics: Small Animal …, 2017 - vetsmall.theclinics.com
The use of intravenous lipid emulsions (ILEs) in human clinical toxicology has become
common practice as a life-saving treatment of local anesthetic–induced cardiotoxicity …

Clinical pharmacology of local anesthetics

JF Butterworth - Neural Blockade in Clinical Anaesthesia and …, 2009 - books.google.com
A review of the clinical pharmacology of local anesthetics must consider those factors that
influence the usefulness and toxicity of the drugs as a group, as well as those factors specific …