Wound care is a major healthcare expenditure. Treatment of burns, surgical and trauma
wounds, diabetic lower limb ulcers and skin wounds is a major medical challenge with …

Zinc is an essential nutrient for human health and has anti-oxidative stress and anti-
inflammatory functions. The association between zinc deficiency and the development of …

Zinc is involved in a variety of biological processes, as a structural, catalytic, and intracellular
and intercellular signaling component. Thus zinc homeostasis is tightly controlled at the …

Zinc (Zn) is an essential micronutrient for plants and animals owing to its structural and
catalytic roles in many proteins. Zn deficiency affects around 2 billion people, mainly those …

Zinc transporter 1 (ZNT1) is the only zinc transporter predominantly located on the plasma
membrane, where it plays a pivotal role exporting cytosolic zinc to the extracellular space …

All organisms must regulate the cellular uptake, efflux, and intracellular trafficking of
essential elements, including d-block metal ions. In bacteria, such regulation is achieved by …

Zinc is an essential cofactor for many proteins. A key mechanism of zinc homeostasis during
deficiency is “zinc sparing” in which specific zinc-binding proteins are repressed to reduce …

Between 5 and 10% of all proteins of a given organism are estimated to require zinc for
function, and hence zinc is essential for almost any given metabolic process. It is therefore of …

Zinc is an essential cofactor required for life and, as such, mechanisms exist for its
homeostatic maintenance in biological systems. Despite the evolutionary distance between …

Epidemiological data have linked cadmium exposure to neurotoxicity and to
neurodegenerative diseases (eg, Alzheimer's and Parkinson's disease), and to increased …