DGKs (diacylglycerol kinases) are members of a unique and conserved family of
intracellular lipid kinases that phosphorylate DAG (diacylglycerol), catalysing its conversion …

Diacylglycerol (DAG) kinase (DGK) modulates the balance between the two signaling lipids,
DAG and phosphatidic acid (PA), by phosphorylating DAG to yield PA. To date, ten …

Ghrelin is an acyl-peptide gastric hormone acting on the pituitary and hypothalamus to
stimulate growth hormone (GH) release, adiposity, and appetite. Ghrelin endocrine activities …

The gastric pathogen Helicobacter pylori translocates the CagA protein into epithelial cells
by a type IV secretion process. Translocated CagA is tyrosine phosphorylated (CagA P‐Tyr) …

Diacylglycerol kinases (DGKs) phosphorylate the second-messenger diacylglycerol (DAG)
to phosphatidic acid (PA). The family of DGKs is well conserved among most species. Nine …

Much is known about how T cell receptor (TCR) engagement leads to T cell activation;
however, the mechanisms terminating TCR signaling remain less clear. Diacylglycerol …

The mammalian diacylglycerol kinases (DGK) are a group of enzymes having important
roles in regulating many biological processes. Both the product and the substrate of these …

Inhibition of αvβ3 integrin or expression of oncogenic mutants of p53 promote invasive cell
migration by enhancing endosomal recycling of α5β1 integrin under control of the Rab11 …

Although diacylglycerol kinase α (DGKα) has been linked to several signaling pathways
related to cancer cell biology, it has been neglected as a target for cancer therapy. The …

Diacylglycerol kinase (DGK) is suggested to attenuate diacylglycerol-induced cell responses
through the phosphorylation of this second messenger to phosphatidic acid. Here, we show …