Results from recent clinical trials of antibodies that target amyloid-β (Aβ) for Alzheimer's
disease have created excitement and have been heralded as corroboration of the amyloid …

Ageing is the primary risk factor for most neurodegenerative diseases, including Alzheimer
disease (AD) and Parkinson disease (PD). One in ten individuals aged≥ 65 years has AD …

Genes play a strong role in Alzheimer's disease (AD), with late-onset AD showing heritability
of 58–79% and early-onset AD showing over 90%. Genetic association provides a robust …

Brain organoids are self-assembled three-dimensional aggregates generated from
pluripotent stem cells with cell types and cytoarchitectures that resemble the embryonic …

The history of Alzheimer's disease (AD) started in 1907, but we needed to wait until the end
of the century to identify the components of pathological hallmarks and genetic subtypes and …

Alzheimer's disease (AD) is a neurodegenerative disorder that causes cognitive decline,
memory loss, and inability to perform everyday functions. Hallmark features of AD …

The past decade has seen the convergence of a series of new insights that arose from
genetic and systems analyses of Alzheimer's disease (AD) with a wealth of epidemiological …

Alzheimer's disease is the most common cause of dementia. It is an increasingly serious
global health problem and has a significant impact on individuals and society. However, the …

The human nervous system is a remarkably complex physiological network that is inherently
challenging to study because of obstacles to acquiring primary samples. Animal models …

Recent years have witnessed the expansion of tissue failures and diseases. The uprising of
regenerative medicine converges the sight onto stem cell-biomaterial based therapy. Tissue …