Kaempferol as a dietary anti-inflammatory agent: current therapeutic standing

W Alam, H Khan, MA Shah, O Cauli, L Saso - Molecules, 2020 - mdpi.com
Inflammation is a physiological response to different pathological, cellular or vascular
damages due to physical, chemical or mechanical trauma. It is characterized by pain …

Epigallocatechin-3-Gallate (EGCG): New therapeutic perspectives for neuroprotection, aging, and neuroinflammation for the modern age

A Payne, S Nahashon, E Taka, GM Adinew… - Biomolecules, 2022 - mdpi.com
Alzheimer's and Parkinson's diseases are the two most common forms of neurodegenerative
diseases. The exact etiology of these disorders is not well known; however, environmental …

The epitranscriptome m6A writer METTL3 promotes chemo- and radioresistance in pancreatic cancer cells

K Taketo, M Konno, A Asai… - International …, 2017 - spandidos-publications.com
N 6-methyladenosine (m6A) is the most abundant epitranscriptome modification in
mammalian mRNA. Recent years have seen substantial progress in m6A epitranscriptomics …

The potential role of miRNAs in the pathogenesis of cardiovascular diseases–A focus on signaling pathways interplay

EG Khidr, AI Abulsoud, AA Doghish… - … -Research and Practice, 2023 - Elsevier
For the past two decades since their discovery, scientists have linked microRNAs (miRNAs)
to posttranscriptional regulation of gene expression in critical cardiac physiological and …

Attenuation of lipopolysaccharide-induced acute lung injury by hispolon in mice, through regulating the TLR4/PI3K/Akt/mTOR and Keap1/Nrf2/HO-1 pathways, and …

CY Huang, JS Deng, WC Huang, WP Jiang, GJ Huang - Nutrients, 2020 - mdpi.com
The anti-inflammatory effect of hispolon has identified it as one of the most important
compounds from Sanghuangporus sanghuang. The research objectives were to study this …

Kaempferol and inflammation: From chemistry to medicine

KP Devi, DS Malar, SF Nabavi, A Sureda, J Xiao… - Pharmacological …, 2015 - Elsevier
Inflammation is an important process of human healing response, wherein the tissues
respond to injuries induced by many agents including pathogens. It is characterized by pain …

Role of lactate in inflammatory processes: friend or foe

C Manosalva, J Quiroga, AI Hidalgo, P Alarcón… - Frontiers in …, 2022 - frontiersin.org
During an inflammatory process, shift in the cellular metabolism associated with an increase
in extracellular acidification are well-known features. This pH drop in the inflamed tissue is …

Anti-inflammatory therapeutic mechanisms of natural products: insight from rosemary diterpenes, carnosic acid and carnosol

S Habtemariam - Biomedicines, 2023 - mdpi.com
Carnosic acid (CA) and carnosol (CAR) are two major diterpenes of the rosemary plant
(Rosmarinus officinalis). They possess a phenolic structural moiety and are endowed with …

The potential role of flavonoids in ameliorating diabetic cardiomyopathy via alleviation of cardiac oxidative stress, inflammation and apoptosis

FF Jubaidi, S Zainalabidin, IS Taib, ZA Hamid… - International journal of …, 2021 - mdpi.com
Diabetic cardiomyopathy is one of the major mortality risk factors among diabetic patients
worldwide. It has been established that most of the cardiac structural and functional …

Potential valorization of edible nuts by-products: exploring the immune-modulatory and antioxidants effects of selected nut shells extracts in relation to their metabolic …

MA Salem, NM Aborehab, AA Al-Karmalawy, AR Fernie… - Antioxidants, 2022 - mdpi.com
The immune system is a potent army that defends our body against various infections and
diseases through innate and adaptive immunity. Herbal medicine is one of the essential …