A user's guide to golden gate cloning methods and standards

JE Bird, J Marles-Wright, A Giachino - ACS Synthetic Biology, 2022 - ACS Publications
The continual demand for specialized molecular cloning techniques that suit a broad range
of applications has driven the development of many different cloning strategies. One method …

Plant synthetic biology innovations for biofuels and bioproducts

Y Yang, TA Chaffin, AH Ahkami, E Blumwald… - Trends in …, 2022 - cell.com
Plant-based biosynthesis of fuels, chemicals, and materials promotes environmental
sustainability, which includes decreases in greenhouse gas emissions, water pollution, and …

TIR domains of plant immune receptors are 2′, 3′-cAMP/cGMP synthetases mediating cell death

D Yu, W Song, EYJ Tan, L Liu, Y Cao, J Jirschitzka, E Li… - Cell, 2022 - cell.com
Summary 2′, 3′-cAMP is a positional isomer of the well-established second messenger
3′, 5′-cAMP, but little is known about the biology of this noncanonical cyclic nucleotide …

Pathogen effector recognition-dependent association of NRG1 with EDS1 and SAG101 in TNL receptor immunity

X Sun, D Lapin, JM Feehan, SC Stolze… - Nature …, 2021 - nature.com
Plants utilise intracellular nucleotide-binding, leucine-rich repeat (NLR) immune receptors to
detect pathogen effectors and activate local and systemic defence. NRG1 and ADR1 …

A coevolved EDS1-SAG101-NRG1 module mediates cell death signaling by TIR-domain immune receptors

D Lapin, V Kovacova, X Sun, JA Dongus… - The Plant …, 2019 - academic.oup.com
Plant nucleotide binding/leucine-rich repeat (NLR) immune receptors are activated by
pathogen effectors to trigger host defenses and cell death. Toll-interleukin 1 receptor domain …

EDS1 complexes are not required for PRR responses and execute TNL‐ETI from the nucleus in Nicotiana benthamiana

J Zönnchen, J Gantner, D Lapin, K Barthel… - New …, 2022 - Wiley Online Library
Heterodimeric complexes incorporating the lipase‐like proteins EDS1 with PAD4 or SAG101
are central hubs in plant innate immunity. EDS1 functions encompass signal relay from TIR …

Enabling one-pot Golden Gate assemblies of unprecedented complexity using data-optimized assembly design

JM Pryor, V Potapov, RB Kucera, K Bilotti, EJ Cantor… - PLoS …, 2020 - journals.plos.org
DNA assembly is an integral part of modern synthetic biology, as intricate genetic
engineering projects require robust molecular cloning workflows. Golden Gate assembly is a …

An EDS1-SAG101 Complex Is Essential for TNL-Mediated Immunity in Nicotiana benthamiana

J Gantner, J Ordon, C Kretschmer, R Guerois… - The Plant …, 2019 - academic.oup.com
Heterodimeric complexes containing the lipase-like protein ENHANCED DISEASE
SUSCEPTIBILITY1 (EDS1) are regarded as central regulators of plant innate immunity. In …

Highly efficient multiplex editing: one‐shot generation of 8× Nicotiana benthamiana and 12× Arabidopsis mutants

J Stuttmann, K Barthel, P Martin, J Ordon… - The Plant …, 2021 - Wiley Online Library
Genome editing by RNA‐guided nucleases, such as SpCas9, has been used in numerous
different plant species. However, to what extent multiple independent loci can be targeted …

IQ67 DOMAIN proteins facilitate preprophase band formation and division-plane orientation

P Kumari, P Dahiya, P Livanos, L Zergiebel, M Kölling… - Nature plants, 2021 - nature.com
Spatiotemporal control of cell division is essential for the growth and development of
multicellular organisms. In plant cells, proper cell plate insertion during cytokinesis relies on …