Greening reversed-phase liquid chromatography methods using alternative solvents for pharmaceutical analysis

M Yabré, L Ferey, IT Somé, K Gaudin - Molecules, 2018 - mdpi.com
The greening of analytical methods has gained increasing interest in the field of
pharmaceutical analysis to reduce environmental impacts and improve the health safety of …

Exploring the potential of green chemistry in reversed-phase liquid chromatography: A review of sustainable solvents

O Kalisz, M Tobiszewski, A Nowaczyk… - TrAC Trends in Analytical …, 2024 - Elsevier
This article delves into the growing field of green analytical chemistry, focusing on
sustainable solvents for reversed-phase liquid chromatography (RP LC). RP LC is a widely …

Drop-on-powder 3D printing of tablets with an anti-cancer drug, 5-fluorouracil

K Shi, DK Tan, A Nokhodchi, M Maniruzzaman - Pharmaceutics, 2019 - mdpi.com
This study reports the first case of an innovative drop-on-powder (DoP) three-dimensional
(3D) printing technology to produce oral tablets (diameters of 10 mm and 13 mm) loaded …

[HTML][HTML] 5-Fluorouracil-containing inorganic iron oxide/platinum nanozymes with dual drug delivery and enzyme-like activity for the treatment of breast cancer

Z Nie, Y Vahdani, WC Cho, SH Bloukh, Z Edis… - Arabian Journal of …, 2022 - Elsevier
Intrinsic enzyme-mimic activity of inorganic nanoparticles has been widely used for
nanozymatic anticancer and antibacterial treatment. However, the relatively low peroxidase …

Solubility and decomposition of organic compounds in subcritical water

E Yabalak, S Akay, B Kayan, AM Gizir, Y Yang - Molecules, 2023 - mdpi.com
In this article, studies on organic solubility and stability in subcritical water reported during
the past 25 years have been reviewed. Data on the solubility and decomposition of organic …

Comparative degradation of 5-fluorouracil in aqueous solution by using H2O2-modified subcritical water, photocatalytic oxidation and electro-Fenton processes

E Kulaksız, B Kayan, B Gözmen, D Kalderis… - Environmental …, 2022 - Elsevier
This study investigated the degradation of the antineoplastic agent 5-fluorouracil (5-FU)
widely applied to treat different cancers using different advanced oxidation processes such …

Measurement and correlation of the solubility of 5-fluorouracil in pure and binary solvents

RI Zorrilla-Veloz, T Stelzer… - Journal of Chemical & …, 2018 - ACS Publications
The solubility of 5-fluorouracil (5-FU), a widely used chemotherapeutic agent to treat solid
tumors, which include colorectal, head and neck, breast, and lung cancer, was determined …

Solubility and dissolution thermodynamics of 5-fluorouracil in (ethanol+ water) mixtures

S Akay, B Kayan, A Jouyban, F Martínez - Journal of Molecular Liquids, 2021 - Elsevier
Equilibrium mole fraction solubility of 5-fluorouracil (5-FU) in 19 aqueous-ethanolic mixtures,
as well as in neat water and neat ethanol, was determined at seven temperatures from …

Experimental analysis and modeling of aprepitant (an antiemetic drug for chemotherapy) solubility in subcritical water with/without co-solvent

HS Mohammadi, AH Asl, M Khajenoori - The Journal of Supercritical Fluids, 2024 - Elsevier
This action described the experimental equilibrium solubility of aprepitant (APT), an
antiemetic drug for chemotherapy, in subcritical water (SW) with/without ethanol as co …

[HTML][HTML] Dextran-coated iron oxide nanoparticles loaded with 5-fluorouracil for drug-delivery applications

D Predoi, M Balas, MA Badea, SC Ciobanu, N Buton… - Nanomaterials, 2023 - mdpi.com
This study aims to design and test different formulations composed of dextran-coated iron
oxide nanoparticles (IONPs) loaded with 5-Fluorouracil (5-FU) with varying nanoparticle …