[HTML][HTML] In vivo methods and applications of xenon-129 magnetic resonance

H Marshall, NJ Stewart, HF Chan, M Rao… - Progress in Nuclear …, 2021 - Elsevier
Hyperpolarised gas lung MRI using xenon-129 can provide detailed 3D images of the
ventilated lung airspaces, and can be applied to quantify lung microstructure and detailed …

Lung MRI with hyperpolarised gases: current & future clinical perspectives

NJ Stewart, LJ Smith, HF Chan… - The British Journal of …, 2022 - academic.oup.com
The use of pulmonary MRI in a clinical setting has historically been limited. Whilst CT
remains the gold-standard for structural lung imaging in many clinical indications, technical …

Protocols for multi‐site trials using hyperpolarized 129Xe MRI for imaging of ventilation, alveolar‐airspace size, and gas exchange: A position paper from the 129Xe …

PJ Niedbalski, CS Hall, M Castro… - Magnetic resonance …, 2021 - Wiley Online Library
Hyperpolarized (HP) 129Xe MRI uniquely images pulmonary ventilation, gas exchange, and
terminal airway morphology rapidly and safely, providing novel information not possible …

Using hyperpolarized 129Xe MRI to quantify regional gas transfer in idiopathic pulmonary fibrosis

JM Wang, SH Robertson, Z Wang, M He, RS Virgincar… - Thorax, 2018 - thorax.bmj.com
Background Assessing functional impairment, therapeutic response and disease
progression in patients with idiopathic pulmonary fibrosis (IPF) continues to be challenging …

Diverse cardiopulmonary diseases are associated with distinct xenon magnetic resonance imaging signatures

Z Wang, EA Bier, A Swaminathan… - European …, 2019 - Eur Respiratory Soc
Background As an increasing number of patients exhibit concomitant cardiac and pulmonary
disease, limitations of standard diagnostic criteria are more frequently encountered. Here …

Quantitative analysis of hyperpolarized 129Xe gas transfer MRI

Z Wang, SH Robertson, J Wang, M He… - Medical …, 2017 - Wiley Online Library
Purpose Hyperpolarized 129Xe magnetic resonance imaging (MRI) using Dixon‐based
decomposition enables single‐breath imaging of 129Xe in the airspaces, interstitial barrier …

Hyperpolarised 129Xe magnetic resonance imaging to monitor treatment response in children with cystic fibrosis

JH Rayment, MJ Couch, N McDonald… - European …, 2019 - Eur Respiratory Soc
Pulmonary magnetic resonance imaging using hyperpolarised 129Xe gas (XeMRI) can
quantify ventilation inhomogeneity by measuring the percentage of unventilated lung …

Free-breathing Dynamic 19F Gas MR Imaging for Mapping of Regional Lung Ventilation in Patients with COPD

M Gutberlet, TF Kaireit, A Voskrebenzev, F Lasch… - Radiology, 2018 - pubs.rsna.org
Purpose To quantify regional lung ventilation in patients with chronic obstructive pulmonary
disease (COPD) by using free-breathing dynamic fluorinated (fluorine 19 [19F]) gas …

129Xe and Free‐Breathing 1H Ventilation MRI in Patients With Cystic Fibrosis: A Dual‐Center Study

H Marshall, A Voskrebenzev, LJ Smith… - Journal of Magnetic …, 2023 - Wiley Online Library
Background Free‐breathing 1H ventilation MRI shows promise but only single‐center
validation has yet been performed against methods which directly image lung ventilation in …

New developments in imaging idiopathic pulmonary fibrosis with hyperpolarized xenon magnetic resonance imaging

JG Mammarappallil, L Rankine, JM Wild… - Journal of thoracic …, 2019 - journals.lww.com
Idiopathic pulmonary fibrosis (IPF) is a progressive pulmonary disease that is ultimately fatal.
Although the diagnosis of IPF has been revolutionized by high-resolution computed …