Is It Possible to Predict the Odor of a Molecule on the Basis of its Structure?
The olfactory sense is the dominant sensory perception for many animals. When Richard
Axel and Linda B. Buck received the Nobel Prize in 2004 for discovering the G protein …
Axel and Linda B. Buck received the Nobel Prize in 2004 for discovering the G protein …
DoOR 2.0 - Comprehensive Mapping of Drosophila melanogaster Odorant Responses
D Münch, CG Galizia - Scientific reports, 2016 - nature.com
Odors elicit complex patterns of activated olfactory sensory neurons. Knowing the complete
olfactome, ie the responses in all sensory neurons for all relevant odorants, is desirable to …
olfactome, ie the responses in all sensory neurons for all relevant odorants, is desirable to …
The perceptual logic of smell
Highlights•Molecular and anatomical data imply high dimensionality in olfactory perception.•
Psychophysics uncover low dimensionality in olfactory perception.•Physicochemical odor …
Psychophysics uncover low dimensionality in olfactory perception.•Physicochemical odor …
Implausibility of the vibrational theory of olfaction
The vibrational theory of olfaction assumes that electron transfer occurs across odorants at
the active sites of odorant receptors (ORs), serving as a sensitive measure of odorant …
the active sites of odorant receptors (ORs), serving as a sensitive measure of odorant …
Smell compounds classification using UMAP to increase knowledge of odors and molecular structures linkages
M Rugard, T Jaylet, O Taboureau, A Tromelin… - PloS one, 2021 - journals.plos.org
This study aims to highlight the relationships between the structure of smell compounds and
their odors. For this purpose, heterogeneous data sources were screened, and 6038 …
their odors. For this purpose, heterogeneous data sources were screened, and 6038 …
Odorant receptors of Drosophila are sensitive to the molecular volume of odorants
M Saberi, H Seyed-Allaei - Scientific reports, 2016 - nature.com
Which properties of a molecule define its odor? This is a basic yet unanswered question
regarding the olfactory system. The olfactory system of Drosophila has a repertoire of …
regarding the olfactory system. The olfactory system of Drosophila has a repertoire of …
Use of machine learning to identify novel, behaviorally active antagonists of the insect odorant receptor co-receptor (Orco) subunit
D Kepchia, P Xu, R Terryn, A Castro, SC Schürer… - Scientific reports, 2019 - nature.com
Olfaction is a key component of the multimodal approach used by mosquitoes to target and
feed on humans, spreading various diseases. Current repellents have drawbacks …
feed on humans, spreading various diseases. Current repellents have drawbacks …
A spiking neural network model of self-organized pattern recognition in the early mammalian olfactory system
Olfactory sensory information passes through several processing stages before an odor
percept emerges. The question how the olfactory system learns to create odor …
percept emerges. The question how the olfactory system learns to create odor …
Sequence-based prediction of olfactory receptor responses
Computational prediction of how strongly an olfactory receptor (OR) responds to various
odors can help in bridging the widening gap between the large number of receptors that …
odors can help in bridging the widening gap between the large number of receptors that …
The Monte Carlo method as a tool to build up predictive QSPR/QSAR
AA Toropov, AP Toropova - Current Computer-Aided Drug …, 2020 - ingentaconnect.com
Background: The Monte Carlo method has a wide application in various scientific
researches. For the development of predictive models in a form of the quantitative structure …
researches. For the development of predictive models in a form of the quantitative structure …