[HTML][HTML] Hox genes in development and beyond

KA Hubert, DM Wellik - Development, 2023 - journals.biologists.com
Hox genes encode evolutionarily conserved transcription factors that are essential for the
proper development of bilaterian organisms. Hox genes are unique because they are …

Spiralian genomics and the evolution of animal genome architecture

IJY Liao, TM Lu, ME Chen, YJ Luo - Briefings in Functional …, 2023 - academic.oup.com
Recent developments in sequencing technologies have greatly improved our knowledge of
phylogenetic relationships and genomic architectures throughout the tree of life. Spiralia, a …

Positional information and stem cells combine to result in planarian regeneration

PW Reddien - Cold Spring Harbor Perspectives in …, 2022 - cshperspectives.cshlp.org
The capacity for regeneration is broad in the animal kingdom. Planarians are flatworms that
can regenerate any missing body part and their regenerative powers have combined with …

Wnt/β-catenin signalling is required for pole-specific chromatin remodeling during planarian regeneration

E Pascual-Carreras, M Marín-Barba… - Nature …, 2023 - nature.com
For successful regeneration, the identity of the missing tissue must be specified according to
the pre-existing tissue. Planarians are ideal for the study of the mechanisms underlying this …

Identification of putative enhancer-like elements predicts regulatory networks active in planarian adult stem cells

J Neiro, D Sridhar, A Dattani, A Aboobaker - Elife, 2022 - elifesciences.org
Planarians have become an established model system to study regeneration and stem cells,
but the regulatory elements in the genome remain almost entirely undescribed. Here, by …

[HTML][HTML] Nature's Secret Neuro-Regeneration Pathway in Axolotls, Polychaetes and Planarians for Human Therapeutic Target Pathways

NI Mansor, TN Balqis, MN Lani, KL Lye… - International Journal of …, 2024 - mdpi.com
Despite significant improvements in the comprehension of neuro-regeneration, restoring
nerve injury in humans continues to pose a substantial therapeutic difficulty. In the …

Spatial Colinear but Broken Temporal Expression of Duplicated ParaHox Genes in Asexually Reproducing Annelids, Nais communis and Pristina longiseta

RP Kostyuchenko, AV Amosov - Genes, 2023 - mdpi.com
ParaHox genes are key developmental regulators involved in the patterning of the digestive
tract along the anteroposterior axis and the development of the nervous system. Most …

[HTML][HTML] The known, unknown, and unknown unknowns of cell-cell communication in planarian regeneration

JJ Chen, K Lei - Zoological Research, 2023 - ncbi.nlm.nih.gov
Planarians represent the most primitive bilateral triploblastic animals. Most planarian
species exhibit mechanisms for whole-body regeneration, exemplified by the regeneration …

Environmental and molecular regulation of asexual reproduction in the sea anemone Nematostella vectensis

L Al-Shaer, W Leach, N Baban… - Royal Society …, 2023 - royalsocietypublishing.org
Cnidarians exhibit incredible reproductive diversity, with most capable of sexual and
asexual reproduction. Here, we investigate factors that influence asexual reproduction in the …

Cell contractility in early animal evolution

T Brunet - Current Biology, 2023 - cell.com
Tissue deformation mediated by collective cell contractility is a signature characteristic of
animals. In most animals, fast and reversible contractions of muscle cells mediate behavior …