Gynecologic cancers involve the female genital organs, such as the vulva, vagina, cervix,
endometrium, ovaries, and fallopian tubes. The occurrence and frequency of gynecologic …

Mesenchymal stem cells (MSCs) are known as promising sources for cancer therapy and
can be utilized as vehicles in cancer gene therapy. MSC-derived exosomes are central …

While immunosuppressive environments mediated by myeloid-derived suppressor cells
(MDSCs) have been well documented in glioma patients, the mechanisms of MDSC …

An outstanding characteristic of gliomas is their infiltration into brain parenchyma, a property
that impairs complete surgical resection; consequently, these tumors might recur, resulting in …

Cell metabolism can be reprogrammed by tissue hypoxia leading to cell transformation and
glioblastoma multiforme (GBM) progression. In response to hypoxia, GBM cells are able to …

Melanoma is a highly aggressive cancer with high mortality in advanced stages. Metformin
is an oral biguanide drug used for diabetes and has demonstrated positive effects on cancer …

Here we describe isolation and characterization of macrophage-tumor cell fusions (MTFs)
from the blood of pancreatic ductal adenocarcinoma (PDAC) patients. The MTFs were …

Most gliomas are invasive tumors formed from glial cells and associated with high mortality
rates. In this study, we characterized four glioma cell lines of varying degree of …

Purpose Long non-coding RNAs (lncRNAs) play major roles in the development of several
cancers, including cervical cancer (CC). The purpose of the present study is to explore the …

Among the non-coding RNAs, the aberrant expression of microRNAs (miRNAs) is well
described in the oncology field. It is clear that the altered expression of miRNAs is crucial for …