Cognitive impairment, also known as cognitive decline, can occur gradually or suddenly and
can be temporary or more permanent. It represents an increasingly important public health …

Dietary polyphenols have been the focus of major interest for their potential benefits on
human health. Several preclinical studies have been conducted to provide a rationale for …

Abstract Approximately 90% of alpha-synuclein (α-Synuclein) deposited in Lewy bodies is
phosphorylated at serine 129 suggesting that the accumulation of phosphorylated α …

In a number of neurological diseases including Parkinson's disease (PD), α‑synuclein is
aberrantly folded, forming abnormal oligomers, and amyloid fibrils within nerve cells. Strong …

Background Despite decades of intensive research, to date, there is no accepted diagnosis
for Parkinson's disease (PD) based on biochemical analysis of blood or CSF. However …

Abnormal accumulation and propagation of the neuronal protein α-synuclein has been
hypothesized to underlie the pathogenesis of Parkinson's disease, dementia with Lewy …

Oligomeric forms of amyloid aggregates have been detected in the brains and tissues of
patients suffering from neurodegenerative disorders such as Parkinson's disease, and it is …

Alzheimer's and Parkinson's diseases are the most common neurodegenerative diseases.
They are characterized by protein aggregates and so can be considered as prion-like …

α-Synuclein (α-syn) is a presynaptic protein that regulates the release of neurotransmitters
from synaptic vesicles in the brain. α-Syn aggregates, including Lewy bodies, are features of …

Abstract α-Synuclein (α-syn), a small protein that has the intrinsic propensity to aggregate, is
implicated in several neurodegenerative diseases including Parkinson's disease (PD) …