Hallmarks of intestinal stem cells
Intestinal stem cells (ISCs) are highly proliferative cells that fuel the continuous renewal of
the intestinal epithelium. Understanding their regulatory mechanisms during tissue …
the intestinal epithelium. Understanding their regulatory mechanisms during tissue …
Intestinal cellular heterogeneity and disease development revealed by single-cell technology
Y Wang, W Song, S Yu, Y Liu, YG Chen - Cell Regeneration, 2022 - Springer
The intestinal epithelium is responsible for food digestion and nutrient absorption and plays
a critical role in hormone secretion, microorganism defense, and immune response. These …
a critical role in hormone secretion, microorganism defense, and immune response. These …
Epithelial zonation along the mouse and human small intestine defines five discrete metabolic domains
A key aspect of nutrient absorption is the exquisite division of labour across the length of the
small intestine, with individual nutrients taken up at different proximal: distal positions. For …
small intestine, with individual nutrients taken up at different proximal: distal positions. For …
Intestinal epithelial c-Maf expression determines enterocyte differentiation and nutrient uptake in mice
C Cosovanu, P Resch, S Jordan, A Lehmann… - Journal of Experimental …, 2022 - rupress.org
The primary function of the small intestine (SI) is to absorb nutrients to maintain whole-body
energy homeostasis. Enterocytes are the major epithelial cell type facilitating nutrient …
energy homeostasis. Enterocytes are the major epithelial cell type facilitating nutrient …
[HTML][HTML] Capybara: A computational tool to measure cell identity and fate transitions
Measuring cell identity in development, disease, and reprogramming is challenging as cell
types and states are in continual transition. Here, we present Capybara, a computational tool …
types and states are in continual transition. Here, we present Capybara, a computational tool …
Xenotransplanted human organoids identify transepithelial zinc transport as a key mediator of intestinal adaptation
MES Sampah, H Moore, R Ahmad, J Duess… - Nature …, 2024 - nature.com
Short bowel syndrome (SBS) leads to severe morbidity and mortality. Intestinal adaptation is
crucial in improving outcomes. To understand the human gene pathways associated with …
crucial in improving outcomes. To understand the human gene pathways associated with …
Nutritional Balance Matters: Assessing the Ramifications of Vitamin A Deficiency on Poultry Health and Productivity
Y Shastak, W Pelletier - Poultry, 2023 - mdpi.com
Vitamin A, a critical micronutrient, plays a vital role in maintaining poultry health and
maximizing productivity. This comprehensive review paper conducts a thorough analysis of …
maximizing productivity. This comprehensive review paper conducts a thorough analysis of …
An overview of short-bowel syndrome in pediatric patients: focus on clinical management and prevention of complications
C Caporilli, G Giannì, F Grassi, S Esposito - Nutrients, 2023 - mdpi.com
Short-bowel syndrome (SBS) in pediatric age is defined as a malabsorptive state, resulting
from congenital malformations, significant small intestine surgical resection or disease …
from congenital malformations, significant small intestine surgical resection or disease …
Teduglutide promotes epithelial tight junction pore function in murine short bowel syndrome to alleviate intestinal insufficiency
J Reiner, P Berlin, J Wobar, H Schäffler… - Digestive diseases and …, 2020 - Springer
Background In short bowel syndrome, epithelial surface loss results in impaired nutrient
absorption and may lead to intestinal insufficiency or intestinal failure. Nucleotide …
absorption and may lead to intestinal insufficiency or intestinal failure. Nucleotide …
Short bowel syndrome
BA Shakhsheer, BW Warner - Current treatment options in pediatrics, 2019 - Springer
Purpose of review Short gut syndrome is life-altering and life-threatening disease resulting
most often from massive small bowel resection. Recent advances in understanding of the …
most often from massive small bowel resection. Recent advances in understanding of the …