The endothelium plays a pivotal role in the regulation of vascular tone by synthesizing and
liberating endothelium-derived relaxing factors inclusive of vasodilator prostaglandins (eg …

There is accumulating evidence highlighting a close relationship between inflammation and
coronary microvascular dysfunction (CMD) in various experimental and clinical settings, with …

Background: Recent studies suggested that perivascular components, such as perivascular
adipose tissue (PVAT) and adventitial vasa vasorum (VV), play an important role as a source …

Objectives Whether there are prognostic links between coronary morphologies and coronary
functional abnormalities was examined in ischemia and nonobstructive coronary artery …

Perivascular adipose tissue (PVAT) releases numerous factors and adipokines with
paracrine effects on both vascular structure and function. These effects are variable as they …

Recent clinical trials have highlighted that percutaneous coronary intervention in patients
with stable angina provides limited additional benefits on top of optimal medical therapy …

Objective—Although coronary perivascular adipose tissue (PVAT) may play important roles
as a source of inflammation, the association of coronary PVAT inflammation and coronary …

Aims While patients with acute coronary syndrome (ACS) presenting with non-obstructive
coronary artery disease (CAD) are at high risk for cardiovascular mortality and morbidity …

According to the current paradigm, chronic vascular inflammation plays a central role in the
pathogenesis of atherosclerosis. The plaque progression is typically completed with rupture …

Recent advances in vascular imaging have enabled us to uncover the underlying
mechanisms of vascular diseases both ex vivo and in vivo. In the past decade, efforts have …