Updates on applications of low-viscosity grade Hydroxypropyl methylcellulose in coprocessing for improvement of physical properties of pharmaceutical powders

C Jin, F Wu, Y Hong, L Shen, X Lin, L Zhao… - Carbohydrate Polymers, 2023 - Elsevier
Hydroxypropyl methylcellulose (HPMC) is an important polymeric excipient. Its versatility in
terms of molecular weights and viscosity grades is the basis for its wide and successful …

HPMCAS-Based Amorphous Solid Dispersions in Clinic: A Review on Manufacturing Techniques (Hot Melt Extrusion and Spray Drying), Marketed Products and …

L Corrie, S Ajjarapu, S Banda, M Parvathaneni… - Materials, 2023 - mdpi.com
Today, therapeutic candidates with low solubility have become increasingly common in
pharmaceutical research pipelines. Several techniques such as hot melt extrusion, spray …

[HTML][HTML] Engineering of 3D printed personalized polypills for the treatment of the metabolic syndrome

BJ Anaya, JR Cerda, RM D'Atri, I Yuste… - International Journal of …, 2023 - Elsevier
Metabolic syndrome is a collection of abnormalities, including at least three of the following
insulin resistance, hypertension, dyslipidemia, type 2 diabetes, obesity, inflammation, and …

Two-photon polymerization printing with high metal nanoparticle loading

NI Kilic, GM Saladino, S Johansson… - … Applied Materials & …, 2023 - ACS Publications
Two-photon polymerization (2PP) is an efficient technique to achieve high-resolution, three-
dimensional (3D)-printed complex structures. However, it is restricted to photocurable …

Chitosan and HPMCAS double-coating as protective systems for alginate microparticles loaded with Ctx (Ile21)-Ha antimicrobial peptide to prevent intestinal …

CA Roque-Borda, MMS Saraiva, WDM Junior… - Biomaterials, 2023 - Elsevier
The incorrect use of conventional drugs for both prevention and control of intestinal
infections has contributed to a significant spread of bacterial resistance. In this way, studies …

Curcumin-loaded food-grade nano-silica hybrid material exhibiting improved photodynamic effect and its application for the preservation of small yellow croaker …

L Jiao, Y Li, J Hu, S Zhao, X Zhang, S Benjakul… - Food Research …, 2024 - Elsevier
Two types of curcumin-loaded food-grade nano-silica (F-SiO 2) hybrid materials were
successfully synthesized using the rotary evaporation method (F-SiO 2@ Cur) and the …

[HTML][HTML] Development of raft-forming liquid and chewable tablet formulations incorporating quercetin solid dispersions for treatment of gastric ulcers

S Bunlung, T Nualnoi, O Issarachot… - Saudi Pharmaceutical …, 2021 - Elsevier
Gastroretentive raft-forming formulations were developed in liquid and chewable tablet
dosage forms to achieve prolonged delivery of quercetin in the stomach. The formulations …

Bioavailability improvement of carbamazepine via oral administration of modified-release amorphous solid dispersions in rats

H Li, M Zhang, L Xiong, W Feng, RO Williams III - Pharmaceutics, 2020 - mdpi.com
The purpose of this study was to improve the bioavailability of carbamazepine (CBZ), a
poorly water-soluble antiepileptic drug, via modified-release amorphous solid dispersions …

Development and characterization of co-amorphous griseofulvin/L-leucin by modified solvent processing hot-melt extrusion

I Partheniadis, I Nikolakakis - International Journal of Pharmaceutics, 2024 - Elsevier
Co-amorphous systems (CAMS) were developed between griseofulvin (GRI) and L-leucine
(LEU) at 2: 1 wt ratio, by application of a novel solvent assisted hot-melt extrusion (HME) …

Celecoxib nanoformulations with enhanced solubility, dissolution rate, and oral bioavailability: Experimental approaches over in vitro/in vivo Evaluation

A Arslan, B Yet, E Nemutlu, Y Akdağ Çaylı, H Eroğlu… - Pharmaceutics, 2023 - mdpi.com
Celecoxib (CXB) is a Biopharmaceutical Classification System (BCS) Class II molecule with
high permeability that is practically insoluble in water. Because of the poor water solubility …