The majority of animal phyla have species that can regenerate. Comparing regeneration
across animals can reconstruct the molecular and cellular evolutionary history of this …

While virtually all animals show certain abilities for regeneration after an injury, these
abilities vary greatly among metazoans. Porifera (Sponges) is basal metazoans …

Muscle-based movement is a hallmark of animal biology, but the evolutionary origins of
myocytes are unknown. Although believed to lack muscles, sponges (Porifera) are capable …

Regulated cellular aggregation is an essential process for development and healing in
many animal tissues. In some animals and a few distantly related unicellular species …

Upon injury, the homeostatic balance that ensures tissue function is disrupted. Wound-
induced signaling triggers the recovery of tissue integrity and offers a context to understand …

Throughout the animal kingdom regenerative ability varies greatly from species to species,
and even tissue to tissue within the same organism. The sheer diversity of structures and …

Regenerative potential is widespread but unevenly distributed across animals. However, our
understanding of the molecular mechanisms underlying regenerative processes is limited to …

Sponges are interesting animal models for regeneration studies, since even from
dissociated cells, they are able to regenerate completely. In particular, explants are model …

Background Sponge holobionts (ie, the host and its associated microbiota) play a key role in
the cycling of dissolved organic matter (DOM) in marine ecosystems. On coral reefs, an …

In order to address a biological explanation for the different regenerative abilities present
among animals, a new evolutionary speculation is presented. It is hypothesized that …