High-voltage electrical pulses in oncology: irreversible electroporation, electrochemotherapy, gene electrotransfer, electrofusion, and electroimmunotherapy
B Geboers, HJ Scheffer, PM Graybill, AH Ruarus… - Radiology, 2020 - pubs.rsna.org
This review summarizes the use of high-voltage electrical pulses (HVEPs) in clinical
oncology to treat solid tumors with irreversible electroporation (IRE) and …
oncology to treat solid tumors with irreversible electroporation (IRE) and …
Cardiac ablation with pulsed electric fields: principles and biophysics
Pulsed electric fields (PEFs) have emerged as an ideal cardiac ablation modality. At present
numerous clinical trials in humans are exploring PEF as an ablation strategy for both atrial …
numerous clinical trials in humans are exploring PEF as an ablation strategy for both atrial …
A theoretical argument for extended interpulse delays in therapeutic high-frequency irreversible electroporation treatments
KN Aycock, Y Zhao, MF Lorenzo… - IEEE Transactions on …, 2021 - ieeexplore.ieee.org
High-frequency irreversible electroporation (H-FIRE) is a tissue ablation modality employing
bursts of electrical pulses in a positive phase–interphase delay (d 1)–negative phase …
bursts of electrical pulses in a positive phase–interphase delay (d 1)–negative phase …
Experimental high-frequency irreversible electroporation using a single-needle delivery approach for nonthermal pancreatic ablation in vivo
TJ O'Brien, M Passeri, MF Lorenzo, JK Sulzer… - Journal of Vascular and …, 2019 - Elsevier
Purpose To investigate the feasibility of single-needle high-frequency irreversible
electroporation (SN-HFIRE) to create reproducible tissue ablations in an in vivo pancreatic …
electroporation (SN-HFIRE) to create reproducible tissue ablations in an in vivo pancreatic …
Mathematical modeling of the thermal effects of irreversible electroporation for in vitro, in vivo, and clinical use: a systematic review
P Agnass, E van Veldhuisen… - International journal …, 2020 - Taylor & Francis
Introduction Irreversible electroporation (IRE) is a relatively new ablation method for the
treatment of unresectable cancers. Although the main mechanism of IRE is electric …
treatment of unresectable cancers. Although the main mechanism of IRE is electric …
[HTML][HTML] Irreversible electroporation for locally advanced pancreatic cancer
FEF Timmer, B Geboers, AH Ruarus… - Techniques in vascular …, 2020 - Elsevier
Several minimally invasive image guided tumor ablation techniques have been added to the
treatment spectrum for locally advanced pancreatic cancer (LAPC). Irreversible …
treatment spectrum for locally advanced pancreatic cancer (LAPC). Irreversible …
Median 4‐year outcomes of salvage irreversible electroporation for localized radio‐recurrent prostate cancer
B Geboers, MJ Scheltema, A Blazevski… - BJU …, 2023 - Wiley Online Library
Objectives To evaluate the safety, and short to mid‐term oncological and quality‐of‐life
(QoL) outcomes of focal irreversible electroporation (IRE) for radio‐recurrent prostate cancer …
(QoL) outcomes of focal irreversible electroporation (IRE) for radio‐recurrent prostate cancer …
System and method for ablating a tissue site by electroporation with real-time pulse monitoring
IIR Neal - US Patent 12,114,911, 2024 - Google Patents
A medical system for ablating a tissue site by electroporation with real-time pulse monitoring
during an electroporation treatment procedure is provided. The treatment control module …
during an electroporation treatment procedure is provided. The treatment control module …
Temperature dependence of high frequency irreversible electroporation evaluated in a 3D tumor model
Electroporation is a bioelectric phenomenon used to deliver target molecules into cells in
vitro and irreversible electroporation (IRE) is an emerging cancer therapy used to treat …
vitro and irreversible electroporation (IRE) is an emerging cancer therapy used to treat …
Device and methods for delivery of high frequency electrical pulses for non-thermal ablation
The present invention relates to the field of biomedical engineering and medical treatment of
diseases and disorders. Methods, devices, and systems for in vivo treatment of cell …
diseases and disorders. Methods, devices, and systems for in vivo treatment of cell …