Oxazole and isoxazole: From one-pot synthesis to medical applications

A Thakur, M Verma, R Bharti, R Sharma - Tetrahedron, 2022 - Elsevier
N, O-containing five-membered heterocycles especially oxazole and isoxazole, have widely
been found in many natural products and drugs with relevant medicinal and pharmaceutical …

Advances in the synthetic strategies of benzoxazoles using 2-aminophenol as a precursor: an up-to-date review

S Soni, N Sahiba, S Teli, P Teli, LK Agarwal… - RSC advances, 2023 - pubs.rsc.org
Benzoxazole is a resourceful and important member of the heteroarenes that connects
synthetic organic chemistry to medicinal, pharmaceutical, and industrial areas. It is a bicyclic …

Mechanochemical Solvent‐Free Catalytic C− H Methylation

S Ni, M Hribersek, SK Baddigam… - Angewandte Chemie …, 2021 - Wiley Online Library
The mechanochemical, solvent‐free, highly regioselective, rhodium‐catalyzed C− H
methylation of (hetero) arenes is reported. The reaction shows excellent functional‐group …

A review of recent synthetic strategies and biological activities of isoxazole

CP Pandhurnekar, HC Pandhurnekar… - Journal of …, 2023 - Wiley Online Library
Among different heterocyclic compounds, isoxazole and their analogues are very important
classes of heterocyclic compounds as they display an extensive range of biological actions …

Substituent-Controlled Regioselective Photoinduced Cyclization of N-Allylbenzamides with N-Sulfonylaminopyridinium Salts

C Pan, Z Yang, X Wu, JT Yu, C Zhu - Organic Letters, 2023 - ACS Publications
The annulation reactions of N-allylbenzamides with N-sulfonylaminopyridinium salts were
developed under metal-free photoinduced mild conditions. Substituent-controlled …

[HTML][HTML] 1, 3, 4-Oxadiazole-containing hybrids as potential anticancer agents: Recent developments, mechanism of action and structure-activity relationships

S Nayak, SL Gaonkar, EA Musad… - Journal of Saudi Chemical …, 2021 - Elsevier
Chemotherapy is an important therapeutic approach for the treatment of cancer. Currently,
many anticancer drugs are available in the market that plays an important role in cancer …

Bioinspired heterocyclic compounds as corrosion inhibitors: a comprehensive review

LKMO Goni, MA Jafar Mazumder… - Chemistry–An Asian …, 2021 - Wiley Online Library
Corrosion is a phenomenon that devastatingly affects innovative, industrial, and mechanical
applications, especially in the oil and gas industries. The corrosion conceivably influences …

Flow synthesis approaches to privileged scaffolds–recent routes reviewed for green and sustainable aspects

AI Alfano, M Brindisi, H Lange - Green Chemistry, 2021 - pubs.rsc.org
Privileged scaffolds as starting points toward biologically active molecules represent a
neuralgic point in drug discovery. The ability of synthetic chemists concerned with their …

Visible-light 2, 4-dinitrophenol-mediated photoannulation of α-azidochalcones into 2, 5-diaryloxazoles

UD Newar, S Borra, RA Maurya - Organic Letters, 2022 - ACS Publications
A novel and efficient visible-light 2, 4-dinitrophenol (2, 4-DNP) mediated photoannulation of
α-azidochalcones into 2, 5-diaryloxazoles was developed. The carbon–carbon double bond …

Isatin-hydrazide conjugates as potent α-amylase and α-glucosidase inhibitors: Synthesis, structure and in vitro evaluations

I Abbasi, H Nadeem, A Saeed, HAA Kharl, MN Tahir… - Bioorganic …, 2021 - Elsevier
Managing diabetes that is a global life-threatening problem, remains a challenge for the
scientific community. The inhibition of α-amylase and α-glucosidase enzymes which are …