Oxidative stress in malaria: potential benefits of antioxidant therapy
ARQ Gomes, N Cunha, ELP Varela… - International Journal of …, 2022 - mdpi.com
Malaria is an infectious disease and a serious public health problem in the world, with 3.3
billion people in endemic areas in 100 countries and about 200 million new cases each …
billion people in endemic areas in 100 countries and about 200 million new cases each …
The worst things in life are free: the role of free heme in sickle cell disease
OT Gbotosho, MG Kapetanaki, GJ Kato - Frontiers in immunology, 2021 - frontiersin.org
Hemolysis is a pathological feature of several diseases of diverse etiology such as
hereditary anemias, malaria, and sepsis. A major complication of hemolysis involves the …
hereditary anemias, malaria, and sepsis. A major complication of hemolysis involves the …
Neutrophils and malaria
EH Aitken, A Alemu, SJ Rogerson - Frontiers in immunology, 2018 - frontiersin.org
Neutrophils are abundant in the circulation and are one of the immune system's first lines of
defense against infection. There has been substantial work carried out investigating the role …
defense against infection. There has been substantial work carried out investigating the role …
Type I interferon transcriptional signature in neutrophils and low-density granulocytes are associated with tissue damage in malaria
BC Rocha, PE Marques, FM de Souza Leoratti… - Cell reports, 2015 - cell.com
Neutrophils are the most abundant leukocyte population in the bloodstream, the primary
compartment of Plasmodium sp. infection. However, the role of these polymorphonuclear …
compartment of Plasmodium sp. infection. However, the role of these polymorphonuclear …
Benign ethnic neutropenia
SA Atallah-Yunes, A Ready, PE Newburger - Blood reviews, 2019 - Elsevier
Benign ethnic neutropenia (BEN) is one of the most common causes of chronic neutropenia
seen in individuals of African, Middle Eastern and West Indian descent, affecting many …
seen in individuals of African, Middle Eastern and West Indian descent, affecting many …
Neutrophils in malaria: A double-edged sword role
KA Babatunde, OF Adenuga - Frontiers in immunology, 2022 - frontiersin.org
Neutrophils are the most abundant leukocytes in human peripheral blood. They form the first
line of defense against invading foreign pathogens and might play a crucial role in malaria …
line of defense against invading foreign pathogens and might play a crucial role in malaria …
Indomethacin impairs mitochondrial dynamics by activating the PKCζ–p38–DRP1 pathway and inducing apoptosis in gastric cancer and normal mucosal cells
S Mazumder, R De, S Debsharma, S Bindu… - Journal of Biological …, 2019 - ASBMB
The subcellular mechanism by which nonsteroidal anti-inflammatory drugs (NSAIDs) induce
apoptosis in gastric cancer and normal mucosal cells is elusive because of the diverse …
apoptosis in gastric cancer and normal mucosal cells is elusive because of the diverse …
Learning from artemisinin: bioinspired design of a reaction-based fluorescent probe for the selective sensing of labile heme in complex biosystems
S Xu, HW Liu, L Chen, J Yuan, Y Liu… - Journal of the …, 2020 - ACS Publications
Labile heme (LH) is an important signaling molecule in virtually all organisms. However,
specifically detecting LH remains an outstanding challenge. Herein, by learning from the …
specifically detecting LH remains an outstanding challenge. Herein, by learning from the …
CXCR4 and MIF are required for neutrophil extracellular trap release triggered by Plasmodium-infected erythrocytes
DAS Rodrigues, EB Prestes, AMS Gama… - PLoS …, 2020 - journals.plos.org
Neutrophil extracellular traps (NETs) evolved as a unique effector mechanism contributing to
resistance against infection that can also promote tissue damage in inflammatory conditions …
resistance against infection that can also promote tissue damage in inflammatory conditions …
Antimalarial activity of small-molecule benzothiazole hydrazones
We synthesized a new series of conjugated hydrazones that were found to be active against
malaria parasite in vitro, as well as in vivo in a murine model. These hydrazones …
malaria parasite in vitro, as well as in vivo in a murine model. These hydrazones …