Extracellular vesicles are a heterogeneous group of membrane-limited vesicles loaded with
various proteins, lipids, and nucleic acids. Release of extracellular vesicles from its cell of …

Extracellular vesicles (EVs) are lipid‐membrane enclosed nanoparticles that play significant
roles in health and disease. EVs are abundant in body fluids and carry an array of molecules …

Tumor-released RNA may mediate intercellular communication and serve as biomarkers.
Here we develop a protocol enabling quantitative, minimally biased analysis of extracellular …

An effective immune response requires the engagement of host receptors by pathogen‐
derived molecules and the stimulation of an appropriate cellular response. Therefore, a …

Exosomes and microvesicles are two major categories of extracellular vesicles (EVs)
released by almost all cell types and are highly abundant in biological fluids. Both the …

Stromal communication with cancer cells can influence treatment response. We show that
stromal and breast cancer (BrCa) cells utilize paracrine and juxtacrine signaling to drive …

Semen contains relatively ill-defined regulatory components that likely aid fertilization, but
which could also interfere with defense against infection. Each ejaculate contains trillions of …

Harnessing exosomes as therapeutic drug delivery vehicles requires a better understanding
of exosomal composition and their mode of action. A full appreciation of all the exosomal …

The discovery of microRNA (miRNA) sorting into extracellular vesicles (EVs) revealed a
novel mode of intercellular communication and uncovered a link between cellular …

Microvesicles represent a newly identified mechanism of intercellular communication. Two
different types of microvesicles have been identified: membrane-derived vesicles (EVs) and …