Cardiovascular risk stratification in familial hypercholesterolaemia

M Sharifi, RD Rakhit, SE Humphries, D Nair - Heart, 2016 - heart.bmj.com
Familial hypercholesterolaemia (FH) is a common autosomal-dominant disorder in most
European countries. Patients with FH are characterised by a raised level of low-density …

Stratification in heterozygous familial hypercholesterolemia: imaging, biomarkers, and genetic testing

P Corral, CA Aguilar Salinas, MG Matta, V Zago… - Current Atherosclerosis …, 2023 - Springer
Abstract Purpose of Review Heterozygous familial hypercholesterolemia (HeFH) is the most
common monogenic autosomal dominant disorder. However, the condition is often …

[HTML][HTML] Cardiovascular health effects of shift work with long working hours and night shifts: study protocol for a three-year prospective follow-up study on industrial …

LK Lunde, Ø Skare, A Mamen, PA Sirnes… - International journal of …, 2020 - mdpi.com
There is a plausible association between shift work and cardiovascular disease (CVD),
which may be due to disruption of the circadian rhythm causing hormonal changes and …

Carotid Plaque Score for Stroke and Cardiovascular Risk Prediction in a Middle‐Aged Cohort From the General Population

H Ihle‐Hansen, T Vigen, T Berge… - Journal of the …, 2023 - Am Heart Assoc
Background We aimed to explore the predictive value of the carotid plaque score, compared
with the Systematic Coronary Risk Evaluation 2 (SCORE2) risk prediction algorithm, on …

[HTML][HTML] Greater preclinical atherosclerosis in treated monogenic familial hypercholesterolemia vs. polygenic hypercholesterolemia

M Sharifi, E Higginson, S Bos, A Gallivan, D Harvey… - Atherosclerosis, 2017 - Elsevier
Background and aims Familial hypercholesterolemia (FH) is a common inherited disorder of
low density lipoprotein-cholesterol (LDL-C) metabolism. It is associated with higher risk of …

Prevalence of carotid plaque in a 63‐to 65‐year‐old Norwegian cohort from the general population: the ACE (Akershus Cardiac Examination) 1950 study

H Ihle‐Hansen, T Vigen, H Ihle‐Hansen… - Journal of the …, 2018 - Am Heart Assoc
Background New data on extracranial carotid atherosclerosis are needed, as improved
ultrasound techniques may detect more atherosclerosis, the definition of plaque has …

The independent and incremental value of ultrasound carotid plaque length to predict the presence and severity of coronary artery disease: analysis from the carotid …

W Tang, X Shen, H Li, Y Bai, B Zhang… - European Heart …, 2020 - academic.oup.com
Aims Data regarding the relationship between carotid plaque length (CPL) and coronary
artery disease (CAD) are lacking. This study aimed to assess the predictive value of CPL for …

Carotid atherosclerosis is associated with middle cerebral artery pulsatility index

T Vigen, H Ihle‐Hansen, MN Lyngbakken… - Journal of …, 2020 - Wiley Online Library
ABSTRACT BACKGROUND AND PURPOSE Pulsatility index (PI) in the middle cerebral
artery (MCA) is considered a measure of peripheral vascular resistance. Several established …

An age-matched computed tomography angiographic study of coronary atherosclerotic plaques in patients with familial hypercholesterolaemia

J Pang, A Abraham, C Vargas-García, TR Bates… - Atherosclerosis, 2020 - Elsevier
Background and aims Familial hypercholesterolaemia (FH) is characterised by a high, but
variable risk of premature coronary artery disease (CAD). Cardiac computed tomography …

Carotid artery plaques and intima medial thickness in familial hypercholesteraemic patients on long-term statin therapy: A case control study

S Bos, MHC Duvekot, GJR Ten Kate, AJM Verhoeven… - Atherosclerosis, 2017 - Elsevier
Background and aims Statins reduce subclinical atherosclerosis and premature
atherosclerotic cardiovascular disease (ASCVD) in patients with familial …