Prickle is an evolutionarily conserved family of proteins exclusively associated with planar
cell polarity (PCP) signalling. This signalling pathway provides directional and positional …

Abstract Ethnopharmacological relevance Wuzi Yanzong Pill (WYP) is a classic traditional
Chinese medicine (TCM) formula that is used for reproductive system diseases. Previous …

Introduction: In the early stage of embryonic development, the neural tube (NT) cannot be
closed properly due to some complex factors, including environmental factors, genetic …

Neural tube defects (NTDs) are complex congenital malformations resulting from failure of
neural tube closure during embryogenesis, which is affected by the interaction of genetic …

Chemotherapeutic agents such as methotrexate (MTX), raltitrexed (RTX), 5-fluorouracil (5-
FU), hydroxyurea (HU), and retinoic acid (RA), and valproic acid (VPA), an antiepileptic …

Targeting integrin α7 (ITGA7) suppresses malignant progression of several types of cancer,
including tongue squamous cell carcinoma, hepatocellular carcinoma and non-small cell …

Abstract Ethnopharmacological relevance jinkui Shenqi Pill (JSP) is a classic traditional
Chinese medicine used to treat “Kidney Yang Deficiency” disease. Previous studies indicate …

Background: This study explored underlying gene signatures of low birth weight (LBW) by
analyzing differentially expressed genes (DEGs) between LBW and normal birth weight …

目的构建低叶酸联合甲氨蝶呤(methotrexate, MTX) 诱导神经管畸形(neural tube defect, NTDs)
的胎鼠模型中lncRNA 相关的竞争性内源RNA (competing endogenous RNAs, ceRNA) …

Neural tube defects (NTDs) are severe congenital malformations that can lead to lifelong
disability. Wuzi Yanzong Pill (WYP) is an herbal formula of traditional Chinese medicine …