Adnexal masses can have gynecologic or nongynecologic etiologies, ranging from normal
luteal cysts to ovarian cancer to bowel abscesses. Women who report abdominal or pelvic …

Background While the underlying causes of cancer are genetic modifications, changes in
cellular states mediate cancer development. Tumor cells display markedly changed …

Purpose: We aimed to develop an ovarian cancer–specific predictive framework for clinical
stage, histotype, residual tumor burden, and prognosis using machine learning methods …

CA125, human epididymis secretary protein 4 (HE4) and the Risk of Ovarian Malignancy
Algorithm (ROMA) could be used for diagnosing ovarian cancer (OCa). However, it has not …

Gynecological cancers including breast, cervical, ovarian, uterine, and vaginal, pose the
greatest threat to world health, with early identification being crucial to patient outcomes and …

Epithelial ovarian cancer has become the most frequent cause of deaths among
gynecologic malignancies. Our study elucidates the diagnostic performance of Risk of …

Aim To develop and validate a biomarker-based index to optimize referral and diagnosis of
patients with suspected ovarian cancer. Furthermore, to compare this new index with the …

Abstract HE4 (human epididymis protein 4) is overexpressed in both ovarian and
endometrial cancers. Levels of the shed HE4 protein are elevated in sera from ovarian and …

Objectives The aim of this study was to determine whether the Risk of Ovarian Malignancy
Algorithm (ROMA) is more accurate than the human epididymis 4 (HE4) or carbohydrate …

Ovarian carcinoma (OC) is the most lethal gynecological malignancy. Response to platinum-
based chemotherapy is poor in some patients and, thus, current research is focusing on new …