Intra-pancreatic fat deposition: bringing hidden fat to the fore

MS Petrov, R Taylor - Nature Reviews Gastroenterology & Hepatology, 2022 - nature.com
Abstract Development of advanced modalities for detection of fat within the pancreas has
transformed understanding of the role of intra-pancreatic fat deposition (IPFD) in health and …

Metabolic implications of pancreatic fat accumulation

R Wagner, SS Eckstein, H Yamazaki, F Gerst… - Nature Reviews …, 2022 - nature.com
Fat accumulation outside subcutaneous adipose tissue often has unfavourable effects on
systemic metabolism. In addition to non-alcoholic fatty liver disease, which has received …

Fatty change of the pancreas: the Pandora's box of pancreatology

MS Petrov - The Lancet Gastroenterology & Hepatology, 2023 - thelancet.com
Prevention of common diseases of the pancreas or interception of their progression is as
attractive in theory as it is elusive in practice. The fundamental challenge has been an …

Nonalcoholic fatty pancreas disease: role in metabolic syndrome,“prediabetes,” diabetes and atherosclerosis

TD Filippatos, K Alexakis, V Mavrikaki… - Digestive Diseases and …, 2022 - Springer
Fat accumulation in the pancreas associated with obesity and the metabolic syndrome
(MetS) has been defined as “non-alcoholic fatty pancreas disease”(NAFPD). The aim of this …

[HTML][HTML] Uniting epidemiology and experimental models: pancreatic steatosis and pancreatic cancer

E Truong, S Pandol, C Jeon - EBioMedicine, 2022 - thelancet.com
Research from epidemiologic studies and experimental animal models provide insights into
the role of pancreatic steatosis in the development of pancreatic cancer. Epidemiologic data …

[HTML][HTML] Mechanisms linking bariatric surgery to adipose tissue, glucose metabolism, fatty liver disease and gut microbiota

S Latteri, M Sofia, S Puleo, A Di Vincenzo… - … Archives of Surgery, 2023 - Springer
Purpose In the last 20 years, bariatric surgery has achieved an important role in translational
and clinical research because of obesity comorbidities. Initially, a tool to lose weight …

Intrapancreatic fat deposition and nutritional treatment: the role of various dietary approaches

G Della Pepa, D Salamone, R Testa… - Nutrition …, 2023 - academic.oup.com
Ectopic fat accumulation in various organs and tissues, such as the liver, muscle, kidney,
heart, and pancreas, is related to impaired capacity of adipose tissue to accumulate …

Measuring brown fat using MRI and implications in the metabolic syndrome

Q Yu, S Huang, TT Xu, YC Wang… - Journal of Magnetic …, 2021 - Wiley Online Library
Metabolic syndrome is presently becoming a global health concern. Brown adipose tissue
(BAT) has the potential for managing the risk factors of metabolic syndrome by adjusting …

Bariatric surgery and gut-brain-Axis driven alterations in cognition and inflammation

E Custers, A Franco, AJ Kiliaan - Journal of Inflammation Research, 2023 - Taylor & Francis
Obesity is associated with systemic inflammation, comorbidities like diabetes, cardiovascular
disease and several cancers, cognitive decline and structural and functional brain changes …

[HTML][HTML] Fatty pancreas and cardiometabolic risk: response of ectopic fat to lifestyle and surgical interventions

KH Leiu, SD Poppitt, JL Miles-Chan, IR Sequeira - Nutrients, 2022 - mdpi.com
Ectopic fat accumulation in non-adipose organs, such as the pancreas and liver, is
associated with an increased risk of cardiometabolic disease. While clinical trials have …