Anthracycline-based chemotherapy can result in the development of a cumulative and
progressively developing cardiomyopathy. Doxorubicin is one of the most highly prescribed …

Modern cancer therapy has successfully cured many cancers and converted a terminal
illness into a chronic disease. Because cancer patients often have coexisting heart …

Contraction-induced production of reactive oxygen species has been shown to cause
oxidative stress to skeletal muscle. As an adaptive response, muscle antioxidant defense …

Objectives: The purpose of this study was to study the underlying molecular mechanisms of
the protective cardiac effects of physical exercise. Background: Telomere-regulating proteins …

OBJECTIVES: To provide an overview and update of physical activity (PA) research across
the entire cancer control continuum. DATA SOURCES: Previous cancer control frameworks …

Anthracycline-containing chemotherapy (eg, doxorubi-cin) is well known to cause dose-
dependent, progressive cardiac damage clinically manifest as decreased left ventricular …

Cancer and its treatments introduce various adverse effects that may affect survivors'
physical, cognitive and psychological functioning. Frequently both tolerance to activity and …

Doxorubicin-induced cardiotoxicity in childhood cancer survivors is a growing problem. The
population of patients at risk for cardiovascular disease is steadily increasing, as five-year …

Myocardial injury is a major contributor to the morbidity and mortality associated with
coronary artery disease. Regular exercise has been confirmed as a pragmatic …

Because doxorubicin (DOX)-containing chemotherapy causes left ventricular (LV)
dysfunction and remodeling that can progress to heart failure, strategies to alleviate DOX …