LDER-GE estimates phenotypic variance component of gene–environment interactions in human complex traits accurately with GE interaction summary statistics and …

Z Dong, W Jiang, H Li, AT DeWan… - Briefings in …, 2024 - academic.oup.com
Gene–environment (GE) interactions are essential in understanding human complex traits.
Identifying these interactions is necessary for deciphering the biological basis of such traits …

OmeSim: a genetics-based nonlinear simulator for in-between-ome and phenotype

Z Long, Q Zhang - bioRxiv, 2024 - biorxiv.org
Motivation: Deciphering genetic basis of complex traits via genotype-phenotype association
stud-ies is a long-standing theme in genetics. The availability of molecular omics data (such …

Estimating Variant Intolerance for Genes of Cattle

S Lanigan - 2024 - stud.epsilon.slu.se
Cattle play a crucial role in providing nutrition and economic stability worldwide. Threats to
their health, particularly infectious diseases, and genetic mutations, can have profound …