Globally, clear-cell renal cell carcinoma (ccRCC) represents the most prevalent type of
kidney cancer. Surgery plays a key role in the treatment of this cancer, although one third of …

Epithelial–mesenchymal transition (EMT) has been implicated in various aspects of tumor
development, including tumor invasion and metastasis, cancer stemness, and therapy …

Epithelial–mesenchymal transition (EMT) is a cellular process involved in many
physiological and pathological conditions. However, in the last decade there has been a …

Epithelial–mesenchymal transition (EMT) is a reversible cellular process, characterized by
changes in gene expression and activation of proteins, favoring the trans-differentiation of …

Many cancers might be influenced by obesity, including breast cancer, the leading cause of
cancer death among women. Obesity is a complex state associated with multiple …

The acquired ability to induce the formation of a functional vasculature is a hallmark of
cancer. Blood vessels in tumors are formed through various mechanisms, among the most …

Adiposity is associated with an increased risk of various types of carcinoma. One of the
plausible mechanisms underlying the tumor-promoting role of obesity is an aberrant …

Triple-negative breast cancer (TNBC) is one of the most aggressive cancer types with high
recurrence, metastasis, and drug resistance. Recent studies report that long noncoding …

Leptin, a multifunctional hormone primarily, but not exclusively, secreted in adipose tissue, is
implicated in a wide range of biological functions that control different processes, such as …

Excess body weight and obesity have become significant risk factors for cancer
development. During obesity, adipose tissue alters its biological function, deregulating the …