The prefrontal cortex, pathological anxiety, and anxiety disorders
MM Kenwood, NH Kalin, H Barbas - Neuropsychopharmacology, 2022 - nature.com
Anxiety is experienced in response to threats that are distal or uncertain, involving changes
in one's subjective state, autonomic responses, and behavior. Defensive and physiologic …
in one's subjective state, autonomic responses, and behavior. Defensive and physiologic …
The nature and neurobiology of fear and anxiety: State of the science and opportunities for accelerating discovery
Fear and anxiety play a central role in mammalian life, and there is considerable interest in
clarifying their nature, identifying their biological underpinnings, and determining their …
clarifying their nature, identifying their biological underpinnings, and determining their …
[PDF][PDF] Inducing anxiety in large language models increases exploration and bias
Large language models are transforming research on machine learning while galvanizing
public debates. Understanding not only when these models work well and succeed but also …
public debates. Understanding not only when these models work well and succeed but also …
Space, time, and fear: survival computations along defensive circuits
D Mobbs, DB Headley, W Ding, P Dayan - Trends in cognitive sciences, 2020 - cell.com
Naturalistic observations show that decisions to avoid or escape predators occur at different
spatiotemporal scales and that they are supported by different computations and neural …
spatiotemporal scales and that they are supported by different computations and neural …
[HTML][HTML] Fear and anxiety in the face of COVID-19: Negative dispositions towards risk and uncertainty as vulnerability factors
P Millroth, R Frey - Journal of Anxiety Disorders, 2021 - Elsevier
In the face of the COVID-19 pandemic it is important to identify factors that make people
particularly vulnerable of developing mental-health issues in order to provide case-specific …
particularly vulnerable of developing mental-health issues in order to provide case-specific …
[HTML][HTML] Uncertainty as a driver of the youth mental health crisis
Mental health problems in young people have been on the rise for over a decade, with that
trend accelerating during the pandemic. This review proposes that the catalyst effect of the …
trend accelerating during the pandemic. This review proposes that the catalyst effect of the …
The relationships between stress, mental disorders, and epigenetic regulation of BDNF
Z Miao, Y Wang, Z Sun - International journal of molecular sciences, 2020 - mdpi.com
Brain-derived neurotrophic factor (BDNF), a critical member of the neurotrophic family, plays
an important role in multiple stress-related mental disorders. Although alterations in BDNF in …
an important role in multiple stress-related mental disorders. Although alterations in BDNF in …
Investigation on the mental health status of pregnant women in China during the Pandemic of COVID-19
H Dong, R Hu, C Lu, D Huang, D Cui, G Huang… - Archives of gynecology …, 2021 - Springer
Purpose To evaluate the anxiety and depression in pregnant women in China, and its
influencing factors during the corona virus disease 2019 (COVID-19) pandemic. Methods …
influencing factors during the corona virus disease 2019 (COVID-19) pandemic. Methods …
Advances in modeling learning and decision-making in neuroscience
AGE Collins, A Shenhav - Neuropsychopharmacology, 2022 - nature.com
An organism's survival depends on its ability to learn about its environment and to make
adaptive decisions in the service of achieving the best possible outcomes in that …
adaptive decisions in the service of achieving the best possible outcomes in that …
A neural substrate of sex-dependent modulation of motivation
While there is emerging evidence of sex differences in decision-making behavior, the neural
substrates that underlie such differences remain largely unknown. Here we demonstrate that …
substrates that underlie such differences remain largely unknown. Here we demonstrate that …