Chemometric analysis in Raman spectroscopy from experimental design to machine learning–based modeling

S Guo, J Popp, T Bocklitz - Nature protocols, 2021 - nature.com
Raman spectroscopy is increasingly being used in biology, forensics, diagnostics,
pharmaceutics and food science applications. This growth is triggered not only by …

Systematic multi-omics integration (MOI) approach in plant systems biology

IN Jamil, J Remali, KA Azizan… - Frontiers in plant …, 2020 - frontiersin.org
Across all facets of biology, the rapid progress in high-throughput data generation has
enabled us to perform multi-omics systems biology research. Transcriptomics, proteomics …

The power of microbiome studies: some considerations on which alpha and beta metrics to use and how to report results

JG Kers, E Saccenti - Frontiers in microbiology, 2022 - frontiersin.org
Background Since sequencing techniques have become less expensive, larger sample
sizes are applicable for microbiota studies. The aim of this study is to show how, and to what …

So you think you can PLS-DA?

D Ruiz-Perez, H Guan, P Madhivanan, K Mathee… - BMC …, 2020 - Springer
Abstract Background Partial Least-Squares Discriminant Analysis (PLS-DA) is a popular
machine learning tool that is gaining increasing attention as a useful feature selector and …

Integrated omics analysis of specialized metabolism in medicinal plants

A Rai, K Saito, M Yamazaki - The Plant Journal, 2017 - Wiley Online Library
Medicinal plants are a rich source of highly diverse specialized metabolites with important
pharmacological properties. Until recently, plant biologists were limited in their ability to …

Sample size and Shapiro-Wilk test: An analysis for soybean grain yield

RR de Souza, M Toebe, AC Mello… - European Journal of …, 2023 - Elsevier
Ignoring the violation of the error normality assumption is a common mistake that can cause
inconsistencies in the results of the analysis of variance. To avoid this, normality tests such …

Biomarker development for axial spondyloarthritis

MA Brown, Z Li, KAL Cao - Nature Reviews Rheumatology, 2020 - nature.com
The term axial spondyloarthritis (axSpA) encompasses a heterogeneous group of diseases
that have variable presentations, extra-articular manifestations and clinical outcomes, and …

Assessment of premium organic orange juices authenticity using HPLC-HR-MS and HS-SPME-GC-MS combining data fusion and chemometrics

FJ Cuevas, G Pereira-Caro, JM Moreno-Rojas… - Food Control, 2017 - Elsevier
This study aims to develop a robust chemometric approach to make it possible to
authenticate European premium organic orange juices. The metabolomic fingerprinting and …

[HTML][HTML] Multi-omics approach in tea polyphenol research regarding tea plant growth, development and tea processing: Current technologies and perspectives

J Li, Y Wang, JH Suh - Food Science and Human Wellness, 2022 - Elsevier
Polyphenols are one of the most important metabolites in tea due to their unique biological
activities and health benefits, arousing great attention of researchers to investigate …

Biosynthetic regulatory network of flavonoid metabolites in stems and leaves of Salvia miltiorrhiza

H Yang, H Li, Q Li - Scientific Reports, 2022 - nature.com
Flavonoid secondary metabolites can treat and prevent many diseases, but systematic
studies on regulation of the biosynthesis of such metabolites in aboveground parts of Salvia …