Role of SARS-CoV-2 spike-protein-induced activation of microglia and mast cells in the pathogenesis of neuro-COVID
TC Theoharides, D Kempuraj - Cells, 2023 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19). About 45% of COVID-19 patients experience several symptoms a …
disease 2019 (COVID-19). About 45% of COVID-19 patients experience several symptoms a …
Carvacrol—a natural phenolic compound with antimicrobial properties
W Mączka, M Twardawska, M Grabarczyk, K Wińska - Antibiotics, 2023 - mdpi.com
The main purpose of this article is to present the latest research related to selected
biological properties of carvacrol, such as antimicrobial, anti-inflammatory, and antioxidant …
biological properties of carvacrol, such as antimicrobial, anti-inflammatory, and antioxidant …
COVID-19 vaccination in patients with malignancy; a systematic review and meta-analysis of the efficacy and safety
Background Data on the efficacy and safety of COVID-19 vaccines in patients with
malignancy are immature. In this paper, we assessed the literature involving the use of …
malignancy are immature. In this paper, we assessed the literature involving the use of …
[HTML][HTML] Hyper/neuroinflammation in COVID-19 and suicide etiopathogenesis: Hypothesis for a nefarious collision?
A Costanza, A Amerio, A Aguglia, G Serafini… - Neuroscience & …, 2022 - Elsevier
Accumulating scientific and clinical evidence highlighted pathological hyperinflammation as
a cardinal feature of SARS-CoV-2 infection and acute COVID-19 disease. With the …
a cardinal feature of SARS-CoV-2 infection and acute COVID-19 disease. With the …
Recombinant SARS-CoV-2 spike protein stimulates secretion of chymase, tryptase, and IL-1β from human mast cells, augmented by IL-33
I Tsilioni, TC Theoharides - International Journal of Molecular Sciences, 2023 - mdpi.com
SARS-CoV-2 infects cells via its spike (S) protein binding to its surface receptor angiotensin-
converting enzyme 2 (ACE2) and results in the production of multiple proinflammatory …
converting enzyme 2 (ACE2) and results in the production of multiple proinflammatory …
Post-COVID Syndrome: The Research Progress in the Treatment of Pulmonary sequelae after COVID-19 Infection
V Ruggiero, RP Aquino, P Del Gaudio, P Campiglia… - Pharmaceutics, 2022 - mdpi.com
Post-COVID syndrome or long COVID is defined as the persistence of symptoms after
confirmed SARS-CoV-2 infection, the pathogen responsible for coronavirus disease. The …
confirmed SARS-CoV-2 infection, the pathogen responsible for coronavirus disease. The …
Antihistamines improve cardiovascular manifestations and other symptoms of long-COVID attributed to mast cell activation
F Salvucci, R Codella, A Coppola, I Zacchei… - Frontiers in …, 2023 - frontiersin.org
Introduction Long-COVID is a broadly defined condition and there are no effective therapies.
Cardiovascular manifestations of long-COVID include high heart rate, postural tachycardia …
Cardiovascular manifestations of long-COVID include high heart rate, postural tachycardia …
Post-mortem findings of inflammatory cells and the association of 4-hydroxynonenal with systemic vascular and oxidative stress in lethal COVID-19
A recent comparison of clinical and inflammatory parameters, together with biomarkers of
oxidative stress, in patients who died from aggressive COVID-19 and survivors suggested …
oxidative stress, in patients who died from aggressive COVID-19 and survivors suggested …
Time evolution of cytokine profiles associated with mortality in COVID-19 hospitalized patients
L Sanchez-de Prada, O Gorgojo-Galindo… - Frontiers in …, 2022 - frontiersin.org
Background High cytokine levels have been associated with severe COVID-19 disease.
Although many cytokine studies have been performed, not many of them include …
Although many cytokine studies have been performed, not many of them include …
The utility of laboratory parameters for cardiac inflammation in heart failure patients hospitalized with SARS-CoV-2 infection
CN Pilut, C Citu, F Gorun, F Bratosin, OM Gorun… - Diagnostics, 2022 - mdpi.com
COVID-19 has been associated with cardiovascular consequences, including myocardial
infarction, thromboembolic events, arrhythmia, and heart failure. Numerous overlapping …
infarction, thromboembolic events, arrhythmia, and heart failure. Numerous overlapping …