During the past 6 years, there have been substantial advances in our understanding of
human immunodeficiency virus 1 and other viruses, such as hepatitis B virus and hepatitis C …

The new field of viral dynamics, based on within-host modeling of viral infections, began with
models of human immunodeficiency virus (HIV), but now includes many viral infections …

▪ Abstract A viral reservoir is a cell type or anatomical site in association with which a
replication-competent form of the virus accumulates and persists with more stable kinetic …

Highly active antiretroviral therapy (HAART) reduces the viral burden in human
immunodeficiency virus type 1 (HIV-1) infected patients below the threshold of detectability …

HIV-1 eradication from infected individuals has not been achieved with the prolonged use of
highly active antiretroviral therapy (HAART). The cellular reservoir for HIV-1 in resting …

Viral replication and latently infected cellular reservoirs persist in HIV-infected patients
achieving undetectable plasma virus levels with potent antiretroviral therapy. We exploited a …

We used a new real-time polymerase chain reaction (PCR)-based assay that is sensitive,
has a wide dynamic linear range, and is highly reproducible to quantify hepatitis B virus …

Treating HIV-infected patients with a combination of several antiretroviral drugs usually
contributes to a substantial decline in viral load and an increase in CD4+ T cells. However …

Follicular dendritic cells (FDCs) trap Ags and retain them in their native state for many
months. Shortly after infection, HIV particles are trapped on FDCs and can be observed until …

The advent of potent combination antiretroviral therapy has been an important breakthrough
in the treatment of HIV-1 infection, resulting in marked reductions in HIV-1-related morbidity …