Teleost cytotoxic T cells

T Yamaguchi, F Takizawa, M Furihata… - Fish & shellfish …, 2019 - Elsevier
Cell-mediated cytotoxicity is one of the major mechanisms by which vertebrates control
intracellular pathogens. Two cell types are the main players in this immune response …

Progress in PRRSV infection and adaptive immune response mechanisms

H Cai, H Zhang, H Cheng, M Liu, S Wen, J Ren - Viruses, 2023 - mdpi.com
Since its discovery, Porcine reproductive and respiratory syndrome (PRRS) has had a huge
impact on the farming industry. The virus that causes PRRS is Porcine Reproductive and …

Porcine reproductive and respiratory syndrome virus reverse genetics and the major applications

J Chaudhari, HLX Vu - Viruses, 2020 - mdpi.com
Porcine reproductive and respiratory syndrome virus (PRRSV) is a positive sense, single-
stranded RNA virus that is known to infect only pigs. The virus emerged in the late 1980s …

Cellular innate immunity against PRRSV and swine influenza viruses

E Crisci, L Fraile, M Montoya - Veterinary sciences, 2019 - mdpi.com
Porcine respiratory disease complex (PRDC) is a polymicrobial syndrome that results from a
combination of infectious agents, such as environmental stressors, population size …

Porcine reproductive and respiratory syndrome virus: immune escape and application of reverse genetics in attenuated live vaccine development

H Wang, Y Xu, W Feng - Vaccines, 2021 - mdpi.com
Porcine reproductive and respiratory syndrome virus (PRRSV), an RNA virus widely
prevalent in pigs, results in significant economic losses worldwide. PRRSV can escape from …

Adjuvants for swine vaccines: Mechanisms of actions and adjuvant effects

W Charerntantanakul - Vaccine, 2020 - Elsevier
This review deals with mechanisms of actions (MOA) and adjuvant effects of various types of
adjuvants for swine vaccines. A number of different types of adjuvants have been tested with …

Research Progress on the Development of Porcine Reproductive and Respiratory Syndrome Vaccines

H Zhang, Q Luo, Y He, Y Zheng, H Sha, G Li… - Veterinary …, 2023 - mdpi.com
Simple Summary Vaccine immunization measures are mainly adopted for porcine
reproductive and respiratory syndrome (PRRS) prevention. We summarize the advantages …

Cytotoxic T lymphocyte epitopes identified from a contemporary strain of porcine reproductive and respiratory syndrome virus enhance CD4+ CD8+ T, CD8+ T, and γδ …

QM Cao, D Tian, CL Heffron, S Subramaniam… - Virology, 2019 - Elsevier
Immuno-stimulatory class I-restricted cytotoxic T lymphocytes (CTL) epitopes of porcine
reproductive and respiratory syndrome virus (PRRSV) are important for vaccine …

A PRRSV GP5-Mosaic vaccine: Protection of pigs from challenge and ex vivo detection of IFNγ responses against several genotype 2 strains

J Cui, CM O'Connell, A Costa, Y Pan, JA Smyth… - PLoS …, 2019 - journals.plos.org
Porcine reproductive and respiratory syndrome virus (PRRSV), is a highly mutable RNA
virus that affects swine worldwide and its control is very challenging due to its formidable …

Defining correlates of protection for mammalian livestock vaccines against high-priority viral diseases

SK Davis, F Jia, QG Wright, MT Islam, A Bean… - Frontiers in …, 2024 - frontiersin.org
Enhancing livestock biosecurity is critical to safeguard the livelihoods of farmers, global and
local economies, and food security. Vaccination is fundamental to the control and prevention …