Transfusion-related immunomodulation: a reappraisal

LA Youssef, SL Spitalnik - Current opinion in hematology, 2017 - journals.lww.com
Transfusion-related immunomodulation: a reappraisal : Current Opinion in Hematology
Transfusion-related immunomodulation: a reappraisal : Current Opinion in Hematology Log …

Atherogenesis and iron: from epidemiology to cellular level

F Vinchi, MU Muckenthaler, MC Da Silva… - Frontiers in …, 2014 - frontiersin.org
Iron accumulates in human atherosclerotic lesions but whether it is a cause or simply a
downstream consequence of the atheroma formation has been an open question for …

Functional filter for whole-genome sequencing data identifies HHT and stress-associated non-coding SMAD4 polyadenylation site variants> 5 kb from coding DNA

S Xiao, Z Kai, D Murphy, D Li, D Patel… - The American Journal of …, 2023 - cell.com
Despite whole-genome sequencing (WGS), many cases of single-gene disorders remain
unsolved, impeding diagnosis and preventative care for people whose disease-causing …

Bilirubin prevents atherosclerotic lesion formation in low‐density lipoprotein receptor‐deficient mice by inhibiting endothelial VCAM‐1 and ICAM‐1 signaling

ME Vogel, G Idelman, ES Konaniah… - Journal of the American …, 2017 - Am Heart Assoc
Background Numerous epidemiological studies support an inverse association between
serum bilirubin levels and the incidence of cardiovascular disease; however, the mechanism …

Iron loading induces cholesterol synthesis and sensitizes endothelial cells to TNFα-mediated apoptosis

AL Fisher, DN Srole, NJ Palaskas, D Meriwether… - Journal of Biological …, 2021 - ASBMB
In plasma, iron is normally bound to transferrin, the principal protein in blood responsible for
binding and transporting iron throughout the body. However, in conditions of iron overload …

Brain susceptibility to oxidative stress in the perinatal period

S Perrone, LM Tataranno, G Stazzoni… - The Journal of …, 2015 - Taylor & Francis
Oxidative stress (OS) occurs at birth in all newborns as a consequence of the hyperoxic
challenge due to the transition from the hypoxic intrauterine environment to extrauterine life …

Non-transferrin-bound iron in the spotlight: novel mechanistic insights into the vasculotoxic and atherosclerotic effect of iron

F Vinchi - Antioxidants & Redox Signaling, 2021 - liebertpub.com
Significance: While atherosclerosis is an almost inevitable consequence of aging, food
preferences, lack of exercise, and other aspects of the lifestyle in many countries, the …

Acute injury with intravenous iron and concerns regarding long-term safety

K Bishu, R Agarwal - Clinical Journal of the American Society of …, 2006 - journals.lww.com
Intravenous iron is widely used to maintain adequate iron stores and prevent iron deficiency
anemia in patients with chronic kidney disease, yet concerns remain about its long-term …

Low dose iron treatments induce a DNA damage response in human endothelial cells within minutes

IG Mollet, D Patel, FS Govani, A Giess, K Paschalaki… - PLoS …, 2016 - journals.plos.org
Background Spontaneous reports from patients able to report vascular sequelae in real time,
and recognition that serum non transferrin bound iron may reach or exceed 10μmol/L in the …

Signalling, metabolic pathways and iron homeostasis in endothelial cells in health, atherosclerosis and Alzheimer's disease

E Bosseboeuf, C Raimondi - Cells, 2020 - mdpi.com
Endothelial cells drive the formation of new blood vessels in physiological and pathological
contexts such as embryonic development, wound healing, cancer and ocular diseases …