Metformin is the first-line antidiabetic drug and one of the most prescribed medications
worldwide. Because of its ubiquitous occurrence in global waters and demonstrated …

Multi-omics approaches have developed as a profitable technique for plant systems, a
popular method in medical and biological sciences underlining the necessity to outline new …

The antidiabetic drug metformin (MET) and its metabolite guanylurea (GUA) have been
frequently and ubiquitously detected in surface water. Consequently, there has been a …

Metformin is one the most prescribed drug to treat type 2 diabetes. In wastewater treatment
plants, this drug is bacterially transformed to guanylurea, which occurs at higher …

Scientists often set ambitious targets using environmental metabolomics to address
challenging ecotoxicological issues. This promising approach has a high potential to …

Microplastics (MPs) alone may endanger the health and fitness of aquatic species through
different mechanisms. However, the harmful effects of these when mixed with other …

Recent studies have shown guanylurea (GUA) alters the growth and development of fish,
induces oxidative stress, and disrupts the levels and expression of several genes …

The use of human and veterinary drugs has led to the accumulation of pharmaceuticals in
various aquatic environments at progressively increasing levels, exhibiting strong ecological …

The emerging contaminants metformin (MET) and its degradation product guanylurea (GUA)
are released into aquatic environments through wastewater treatment plants (WWTPs) …

Metformin is routinely detected in aquatic ecosystems because of its widespread use as a
treatment for Type 2 diabetes. Laboratory studies have shown that exposure to …