PURPOSE Heightened regulations have decreased opioid prescribing across the United
States, yet little is known about trends in opioid access among patients dying of cancer …

The management of chronic noncancer pain (CNCP) with chronic opioid therapy (COT) is
controversial. There is a lack of consensus on how COT is defined resulting in unclear …

Background Substance use treatment providers have increasingly developed novel
engagement and low-threshold treatment services (such as mobile treatment units) to meet …

Purpose Long-term opioid use for chronic pain has increased, but limited evidence exists on
its benefits. Evaluation of long-term benefits in pain is based on patient-reported measures …

Purpose The purpose of this study was to determine outcomes of an enhanced recovery
pathway (ERP) for minimally invasive repair of pectus excavatum (MIRPE) at a high volume …

Objective Evaluate the association between opioid therapy and healthrelated quality of life
(HRQ oL) in participants with chronic, noncancer pain (CNCP). Data Sources Medical …

Background: Intraoperative resident autonomy has been compromised secondary to
expectations for increased supervision without defined parameters for safe progressive …

The synthetic opioid propoxyphene was a schedule IV controlled substance with multiple
reported health risks before the US Food and Drug Administration issued a request for …

Wnt/β-catenin signaling is involved in various biological processes, including the
development of the central nervous system. The dysfunction of mitochondria has been …

Objective: Experts cautioned that patients affected by the November 2010 withdrawal of the
opioid analgesic propoxyphene might receive riskier prescriptions. To explore this, we …