NATs at a glance
Most proteins receive an acetyl group at the N terminus while in their nascency as the result
of modification by co-translationally acting N-terminal acetyltransferases (NATs). The N …
of modification by co-translationally acting N-terminal acetyltransferases (NATs). The N …
N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity
Most eukaryotic proteins are N-terminally acetylated, but the functional impact on a global
scale has remained obscure. Using genome-wide CRISPR knockout screens in human …
scale has remained obscure. Using genome-wide CRISPR knockout screens in human …
Transition metal anchored on red phosphorus to enable efficient photocatalytic H2 generation
L Lu, M Sun, T Wu, Q Lu, B Chen, CH Chan… - Frontiers in …, 2023 - frontiersin.org
Transition metal (TM) single atom catalysts (SACs) are of great potential for photocatalytic
H2 production because of their abundant catalytic active sites and cost-effectiveness. As a …
H2 production because of their abundant catalytic active sites and cost-effectiveness. As a …
A nonsense variant in the N‐terminal acetyltransferase NAA30 may be associated with global developmental delay and tracheal cleft
S Varland, KM Brønstad, SJ Skinner… - American Journal of …, 2023 - Wiley Online Library
Most human proteins are N‐terminally acetylated by N‐terminal acetyltransferases (NATs),
which play crucial roles in many cellular functions. The NatC complex, comprising the …
which play crucial roles in many cellular functions. The NatC complex, comprising the …
Optimized bisubstrate inhibitors for the actin N-terminal acetyltransferase NAA80
LM Myklebust, M Baumann, SI Støve, H Foyn… - Frontiers in …, 2023 - frontiersin.org
Acetylation of protein N-termini is one of the most common protein modifications in the
eukaryotic cell and is catalyzed by the N-terminal acetyltransferase family of enzymes. The N …
eukaryotic cell and is catalyzed by the N-terminal acetyltransferase family of enzymes. The N …
Molecular Basis for RNA Cytidine Acetylation by NAT10
Human NAT10 acetylates the N4 position of cytidine in RNA, predominantly on rRNA and
tRNA, to facilitate ribosome biogenesis and protein translation. NAT10 has been proposed …
tRNA, to facilitate ribosome biogenesis and protein translation. NAT10 has been proposed …