Small-Conductance Ca2+-Activated K+ Channels: Form and Function

JP Adelman, J Maylie, P Sah - Annual review of physiology, 2012 - annualreviews.org
Small-conductance Ca2+-activated K+ channels (SK channels) are widely expressed
throughout the central nervous system. These channels are activated solely by increases in …

Therapeutic application of anti-arthritis, pain-releasing, and anti-cancer effects of bee venom and its constituent compounds

DJ Son, JW Lee, YH Lee, HS Song, CK Lee… - Pharmacology & …, 2007 - Elsevier
Bee venom (BV) therapy (BVT), the therapeutic application of BV, has been used in
traditional medicine to treat diseases, such as arthritis, rheumatism, pain, cancerous tumors …

Potassium channels: molecular defects, diseases, and therapeutic opportunities

CC Shieh, M Coghlan, JP Sullivan… - Pharmacological …, 2000 - ASPET
Potassium channels play important roles in vital cellular signaling processes in both
excitable and nonexcitable cells. Over 50 human genes encoding various K+ channels have …

Ca2+-activated K+ channels: molecular determinants and function of the SK family

M Stocker - Nature Reviews Neuroscience, 2004 - nature.com
Abstract Ca2+-activated K+ (KCa) channels of small (SK) and intermediate (IK) conductance
are present in a wide range of excitable and non-excitable cells. On activation by low …

Channels underlying neuronal calcium-activated potassium currents

P Sah, ESL Faber - Progress in neurobiology, 2002 - Elsevier
In many cell types rises in cytosolic calcium, either due to influx from the extracellular space,
or by release from an intracellular store activates calcium dependent potassium currents on …

Differential expression of the small-conductance, calcium-activated potassium channel SK3 is critical for pacemaker control in dopaminergic midbrain neurons

J Wolfart, H Neuhoff, O Franz… - Journal of Neuroscience, 2001 - Soc Neuroscience
The physiological activity of dopaminergic midbrain (DA) neurons is important for movement,
cognition, and reward. Altered activity of DA neurons is a key finding in schizophrenia, but …

Calcium-activated potassium channels: multiple contributions to neuronal function

ESL Faber, P Sah - The Neuroscientist, 2003 - journals.sagepub.com
Calcium-activated potassium channels are a large family of potassium channels that are
found throughout the central nervous system and in many other cell types. These channels …

Sarcoplasmic reticulum function in smooth muscle

S Wray, T Burdyga - Physiological reviews, 2010 - journals.physiology.org
The sarcoplasmic reticulum (SR) of smooth muscles presents many intriguing facets and
questions concerning its roles, especially as these change with development, disease, and …

[HTML][HTML] Unique roles of SK and Kv4. 2 potassium channels in dendritic integration

X Cai, CW Liang, S Muralidharan, JPY Kao, CM Tang… - Neuron, 2004 - cell.com
Focal activation of glutamate receptors in distal dendrites of hippocampal pyramidal cells
triggers voltage-dependent Ca 2+ channel-mediated plateau potentials that are confined to …

Physiological role of calcium-activated potassium currents in the rat lateral amygdala

ESL Faber, P Sah - Journal of Neuroscience, 2002 - Soc Neuroscience
Principal neurons in the lateral nucleus of the amygdala (LA) exhibit a continuum of firing
properties in response to prolonged current injections ranging from those that accommodate …