Brain organoid protocols and limitations
HH Zhao, G Haddad - Frontiers in Cellular Neuroscience, 2024 - frontiersin.org
Stem cell-derived organoid technology is a powerful tool that revolutionizes the field of
biomedical research and extends the scope of our understanding of human biology and …
biomedical research and extends the scope of our understanding of human biology and …
Investigating the neurobiology of maternal opioid use disorder and prenatal opioid exposure using brain organoid technology
I Dwivedi, GG Haddad - Frontiers in Cellular Neuroscience, 2024 - frontiersin.org
Over the past two decades, Opioid Use Disorder (OUD) among pregnant women has
become a major global public health concern. OUD has been characterized as a …
become a major global public health concern. OUD has been characterized as a …
Buprenorphine and methadone differentially alter early brain development in human cortical organoids
H Yao, D Hu, J Wang, W Wu, HH Zhao, L Wang… - …, 2023 - Elsevier
Buprenorphine (BUP) and methadone (MTD) are used for medication-assisted treatment
(MAT) in opioid use disorder. Although both medications show improved maternal and …
(MAT) in opioid use disorder. Although both medications show improved maternal and …
Gene association classification for autism spectrum disorder: Leveraging gene embedding and differential gene expression profiles to identify disease-related genes
A Suratanee, K Plaimas - Applied Sciences, 2023 - mdpi.com
Identifying genes associated with autism spectrum disorder (ASD) is crucial for
understanding the underlying mechanisms of the disorder. However, ASD is a complex …
understanding the underlying mechanisms of the disorder. However, ASD is a complex …
Methadone directly impairs central nervous system cells in vitro
C De Gregorio, J Gallardo, P Berríos-Cárcamo… - Scientific Reports, 2024 - nature.com
Methadone is a synthetic long-acting opioid that is increasingly used in the replacement
therapy of opioid-addicted patients, including pregnant women. However, methadone …
therapy of opioid-addicted patients, including pregnant women. However, methadone …
Synapse and primary cilia dysfunctions in Autism Spectrum Disorders. Avenues to normalize these functions
JJ Hauw, C Hausser-Hauw, C Barthélémy - Revue Neurologique, 2024 - Elsevier
Aim An update on the plasticity of the brain networks involved in autism (autism spectrum
disorders [ASD]), and the increasing role of their synapses and primary non-motile cilia …
disorders [ASD]), and the increasing role of their synapses and primary non-motile cilia …
Brain organoid protocols and limitations.
G Haddad, H Zhao - 2024 - escholarship.org
Stem cell-derived organoid technology is a powerful tool that revolutionizes the field of
biomedical research and extends the scope of our understanding of human biology and …
biomedical research and extends the scope of our understanding of human biology and …