In patients with multiple sclerosis (MS), grey matter damage is widespread and might
underlie many of the clinical symptoms, especially cognitive impairment. This relation …

Neuropsychiatric abnormalities may be broadly divided in two categories: disorders of
mood, affect, and behavior and abnormalities affecting cognition. Among these conditions …

Multiple Sclerosis (MS) is a chronic disabling neuroinflammatory disease. Psychiatric
manifestations have a high prevalence in MS patients and may worsen the illness …

Multiple sclerosis (MS) is a chronic disease with an inflammatory and neurodegenerative
pathology. Axonal loss and neurodegeneration occurs early in the disease course and may …

Objective: This study investigates whether changes in functional connectivity, diffusivity, and
volume of the thalamus can explain different severities of cognitive impairment in multiple …

Since its technical development in the early 1980s, magnetic resonance imaging (MRI) has
quickly been adopted as an essential tool in supporting the diagnosis, longitudinal …

Importance Cortical lesions (CLs) contribute to physical and cognitive disability in multiple
sclerosis (MS). Accurate methods for visualization of CLs are necessary for future clinical …

The molecular composition of myelin membranes determines their structure and function.
Even minute changes to the biochemical balance can have profound consequences for …

MRI has become the most important paraclinical tool for diagnosing and monitoring patients
with multiple sclerosis (MS). However, conventional MRI sequences are largely nonspecific …

The importance of macrostructural white matter changes, including white matter lesions and
atrophy, in intact brain functioning is increasingly being recognized. Diffusion tensor imaging …