Abstract The glucagon-like peptide-1 (GLP-1) receptor, known as GLP-1R, is a vital
component of the G protein-coupled receptor (GPCR) family and is found primarily on the …

Background Obesity has reached epidemic proportions, with> 40% of the US population
affected. Although traditionally managed by lifestyle modification, and less frequently by …

Background Obesity is one of the critical public health problems in our society. It leads to
various health conditions, such as type 2 diabetes mellitus, cardiovascular disease …

The objective is to review the newer pharmacological interventions for obesity, specifically
single, dual and triple incretin receptor agonists that are either available or in the pipeline for …

This review highlights how obesity impairs male reproduction through complex mechanisms,
including metabolic syndrome, lipotoxicity, sexual dysfunction, hormonal and adipokine …

Obesity is a chronic disease caused primarily by the imbalance between the amount of
calories supplied to the body and energy expenditure. Not only does it deteriorate the quality …

Introduction Obesity treatment is evolving rapidly with the emergence of agents targeting
incretin receptors. Retatrutide, a triple agonist of these receptors, shows promise in obesity …

The increasing prevalence of obesity and type 2 diabetes mellitus has resulted in a
significant challenge to public health throughout the globe. It required the development of …

Intermolecular interactions are the fabrics underlying almost all processes in living
organisms, where two cornerstone concepts, intermolecular binding affinity (K d) and …

Abstract Background and Aims Overweight and obesity have become global health
challenges with increasing prevalence. Several drugs have received Food and Drug …