Accumulating evidence suggests that the molecular circadian clock is crucial in blood
pressure (BP) control. Circadian rhythms are controlled by the central clock, which resides in …

Adipose tissue (AT) is classified based on its location, physiological and functional
characteristics. Although there is a clear demarcation of anatomical and molecular features …

Optimal vascular structure and function are essential for maintaining the physiological
functions of the cardiovascular system. Vascular remodelling involves changes in vessel …

Obesity epidemic reached the dimensions of a real global health crisis with more than one
billion people worldwide living with obesity. Multiple obesity-related mechanisms cause …

Obesity is a major public health problem and is related to increasing rates of cardiovascular
morbidity and mortality. Over 1.9 billion adults are overweight or obese worldwide and the …

Perivascular adipose tissue (PVAT) refers to the aggregate of adipose tissue surrounding
the vasculature, exhibiting the phenotypes of white, beige and brown adipocytes. PVAT has …

Moyamoya disease is an idiopathic chronically progressive cerebrovascular disease, which
causes both ischemic and hemorrhagic stroke. Genetic studies identified RNF213/Mysterin …

The perivascular adipose tissue (PVAT) is an adipose tissue depot which surrounds most
human blood vessels. It is metabolically active and has both a protective and a pathogenic …

Perivascular adipose tissue (PVAT) is a specialized type of adipose tissue that surrounds
most mammalian blood vessels. PVAT is a metabolically active, endocrine organ capable of …

The incidence of metabolism-related diseases like obesity and type 2 diabetes mellitus has
reached pandemic levels worldwide and increased gradually. Most of them are listed on the …