Current approaches in surgical and immunotherapy-based management of renal cell carcinoma with tumor thrombus
MM Tabbara, J González, M Martucci, G Ciancio - Biomedicines, 2023 - mdpi.com
Renal cell carcinoma (RCC) accounts for 2–3% of all malignant disease in adults, with 30%
of RCC diagnosed at locally advanced or metastatic stages of disease. A form of locally …
of RCC diagnosed at locally advanced or metastatic stages of disease. A form of locally …
Adjuvant therapy for renal cell carcinoma: hype or hope?
F Cosso, G Roviello, G Nesi, S Shabani… - International Journal of …, 2023 - mdpi.com
Renal cell carcinoma (RCC) is the third most common genitourinary cancer accounting for
approximately 180,000 deaths worldwide in 2020. Although over two-thirds of patients …
approximately 180,000 deaths worldwide in 2020. Although over two-thirds of patients …
High risk clear cell renal cell carcinoma microenvironments contain protumour immunophenotypes lacking specific immune checkpoints
AM Raghubar, NA Matigian, J Crawford… - npj Precision …, 2023 - nature.com
Perioperative immune checkpoint inhibitor (ICI) trials for intermediate high-risk clear cell
renal cell carcinoma (ccRCC) have failed to consistently demonstrate improved patient …
renal cell carcinoma (ccRCC) have failed to consistently demonstrate improved patient …
Prognostic Significance of Grade Discrepancy Between Primary Tumor and Venous Thrombus in Nonmetastatic Clear-cell Renal Cell Carcinoma: Analysis of the …
Z Wu, H Chen, Q Chen, S Ge, N Yu, R Campi… - European urology …, 2024 - Elsevier
Background Further stratification of the risk of recurrence of clear-cell renal cell carcinoma
(ccRCC) with venous tumor thrombus (VTT) will facilitate selection of candidates for adjuvant …
(ccRCC) with venous tumor thrombus (VTT) will facilitate selection of candidates for adjuvant …
[HTML][HTML] Cuproptosis-related gene DLAT serves as a prognostic biomarker for immunotherapy in clear cell renal cell carcinoma: multi-database and experimental …
S Huang, C Cai, K Zhou, X Wang, D Cen… - Aging (Albany NY …, 2023 - ncbi.nlm.nih.gov
Objective: Renal clear cell carcinoma (ccRCC) is the most common type of renal cancer.
Here we aim to explore the prognosis and immunotherapeutic value of copper death-related …
Here we aim to explore the prognosis and immunotherapeutic value of copper death-related …
The promise of neoadjuvant and adjuvant therapies for renal cancer
Across a multitude of cancers, extirpative surgery is the cornerstone of treatment for patients
with localized and locally advanced disease. However, a portion of these patients …
with localized and locally advanced disease. However, a portion of these patients …
Prognostic prediction and immunotherapy response analysis of the fatty acid metabolism-related genes in clear cell renal cell carcinoma
Q Yao, X Zhang, C Wei, H Chen, Q Xu, J Chen, D Chen - Heliyon, 2023 - cell.com
Background Clear cell renal cell carcinoma (ccRCC) is a common urinary cancer. Although
diagnostic and therapeutic approaches for ccRCC have been improved, the survival …
diagnostic and therapeutic approaches for ccRCC have been improved, the survival …
Adjuvant therapy for renal cell carcinoma: End points, outcomes, and risk assessments
JJ Boyle, JL Pfail, BJ Lichtbroun, EA Singer - JCO Precision Oncology, 2023 - ascopubs.org
PURPOSE Targeted tyrosine kinase inhibitors (TKIs) and immune-checkpoint inhibitors
(ICIs) revolutionized the treatment of metastatic renal cell carcinoma (RCC). Efforts to …
(ICIs) revolutionized the treatment of metastatic renal cell carcinoma (RCC). Efforts to …
TNM-based risk eligibility for adjuvant trials in renal cell carcinoma
J Bedke, A Bex - The Lancet, 2023 - thelancet.com
Adjuvant therapy in renal cell carcinoma after surgery has been investigated in numerous
clinical trials since the 1990s. However, only two trials have shown an improved disease …
clinical trials since the 1990s. However, only two trials have shown an improved disease …
Bispecific fibrous glue synergistically boosts vascular normalization and antitumor immunity for advanced renal carcinoma therapy
XH Wu, JQ Wang, MD Wang, T Xiao, Y Wang, JY Niu… - Biomaterials, 2024 - Elsevier
Immune checkpoint blockade therapy represented by programmed cell death ligand 1 (PD-
L1) inhibitor for advanced renal carcinoma with an objective response rate (ORR) in patients …
L1) inhibitor for advanced renal carcinoma with an objective response rate (ORR) in patients …