Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

Many species of fungi have been detected in the healthy human gut; however, nearly half of
all taxa reported have only been found in one sample or one study. Fungi capable of …

The nuclear envelope (NE) is a spherical double membrane with elastic properties. How NE
shape and elasticity are regulated by lipid chemistry is unknown. Here we discover lipid acyl …

Objectives Bacteriome and virome alterations are associated with colorectal cancer (CRC).
Nevertheless, the gut fungal microbiota in CRC remains largely unexplored. We aimed to …

Candida albicans is a regular member of the intestinal microbiota in the majority of the
human population. This underscores C. albicans' adaptation to life in the intestine without …

The body is host to a wide variety of microbial communities from which the immune system
protects us and that are important for the normal development of the immune system and for …

In the 21st century, urbanization represents a major demographic shift in developed and
developing countries. Rapid urbanization in the developing world has been associated with …

In a complex, diverse intestinal environment, commensal microbiota metabolizes excessive
dietary tryptophan to produce more bioactive metabolites connecting with kinds of diverse …

Candida species are the most common causes of fungal infection. Approximately 90% of
infections are caused by five species: Candida albicans, Candida glabrata, Candida …

Candida albicans colonization is required for invasive disease,,. Unlike humans, adult mice
with mature intact gut microbiota are resistant to C. albicans gastrointestinal (GI) …