Dialog beyond the grave: necrosis in the tumor microenvironment and its contribution to tumor growth
Damage-associated molecular patterns (DAMPs) are endogenous molecules released from
the necrotic cells dying after exposure to various stressors. After binding to their receptors …
the necrotic cells dying after exposure to various stressors. After binding to their receptors …
Heat shock protein 90: biological functions, diseases, and therapeutic targets
H Wei, Y Zhang, Y Jia, X Chen, T Niu, A Chatterjee… - MedComm, 2024 - Wiley Online Library
Abstract Heat shock protein 90 (Hsp90) is a predominant member among Heat shock
proteins (HSPs), playing a central role in cellular protection and maintenance by aiding in …
proteins (HSPs), playing a central role in cellular protection and maintenance by aiding in …
[HTML][HTML] Targeting apoptosis in clear cell renal cell carcinoma
Clear cell renal cell carcinoma (ccRCC) is the most prevalent subtype of renal cancer,
accounting for approximately 80% of all renal cell cancers. Due to its exceptional inter-and …
accounting for approximately 80% of all renal cell cancers. Due to its exceptional inter-and …
Optimized Microscale Protein Aggregation Suppression Assay: A Method for Evaluating the Holdase Activity of Chaperones
Many molecular chaperones act as holdases by binding hydrophobic regions of substrates
to prevent aggregation. Therefore, measuring holdase activity is an amenable method to …
to prevent aggregation. Therefore, measuring holdase activity is an amenable method to …
Proteomic analysis identifies HMGA2 as a novel biomarker of overall survival in papillary renal cell carcinoma
T Wei, H Xu, H Liang, Y Lian, H Chen, Z Zheng… - Cancer …, 2023 - Wiley Online Library
Purpose Although papillary renal cell carcinoma (PRCC) has a relatively favorable
prognosis, a small number of patients with lymph node or distant metastasis have a poor …
prognosis, a small number of patients with lymph node or distant metastasis have a poor …
[PDF][PDF] 基于网络药理学和细胞实验探讨蟾蜍灵治疗胃癌的作用机制
刘玉玲, 陈利荣, 侯艳香, 王元森 - 天然产物研究与开发 - trcw.ac.cn
To explore the mechanism of action of bufalin in the treatment of gastric cancer based on
network pharmacology, molecular docking and cellular experiments in the study. The …
network pharmacology, molecular docking and cellular experiments in the study. The …
[PDF][PDF] The mechanism of bufalin in the treatment of gastric cancer based on network pharmacology and cellular experiments
LIU Yu-ling, C Li-rong, HOU Yan-xiang… - NATURAL PRODUCT … - trcw.ac.cn
To explore the mechanism of action of bufalin in the treatment of gastric cancer based on
network pharmacology, molecular docking and cellular experiments in the study. The …
network pharmacology, molecular docking and cellular experiments in the study. The …