Tackling the emerging threat of antifungal resistance to human health

MC Fisher, A Alastruey-Izquierdo, J Berman… - Nature reviews …, 2022 - nature.com
Invasive fungal infections pose an important threat to public health and are an under-
recognized component of antimicrobial resistance, an emerging crisis worldwide. Across a …

Immune responses to human fungal pathogens and therapeutic prospects

MS Lionakis, RA Drummond, TM Hohl - Nature Reviews Immunology, 2023 - nature.com
Pathogenic fungi have emerged as significant causes of infectious morbidity and death in
patients with acquired immunodeficiency conditions such as HIV/AIDS and following receipt …

Neglected endemic mycoses

F Queiroz-Telles, AH Fahal, DR Falci… - The Lancet Infectious …, 2017 - thelancet.com
Fungi often infect mammalian hosts via the respiratory route, but traumatic transcutaneous
implantation is also an important source of infections. Environmental exposure to spores of …

Chromoblastomycosis

F Queiroz-Telles, S de Hoog… - Clinical microbiology …, 2017 - Am Soc Microbiol
Chromoblastomycosis (CBM), also known as chromomycosis, is one of the most prevalent
implantation fungal infections, being the most common of the gamut of mycoses caused by …

The pathobiology of human fungal infections

GD Brown, ER Ballou, S Bates, EM Bignell… - Nature Reviews …, 2024 - nature.com
Human fungal infections are a historically neglected area of disease research, yet they
cause more than 1.5 million deaths every year. Our understanding of the pathophysiology of …

The global burden of chromoblastomycosis

DWCL Santos, CMPS de Azevedo… - PLoS Neglected …, 2021 - journals.plos.org
Background Chromoblastomycosis (CBM), represents one of the primary implantation
mycoses caused by melanized fungi widely found in nature. It is characterized as a …

[HTML][HTML] Pattern recognition receptors in fungal immunity

EC Patin, A Thompson, SJ Orr - Seminars in cell & developmental biology, 2019 - Elsevier
Over the last decade, invasive fungal infections have emerged as a growing threat to human
health worldwide and novel treatment strategies are urgently needed. In this context …

Host control of fungal infections: lessons from basic studies and human cohorts

MS Lionakis, SM Levitz - Annual review of immunology, 2018 - annualreviews.org
In the last few decades, the AIDS pandemic and the significant advances in the medical
management of individuals with neoplastic and inflammatory conditions have resulted in a …

Pattern recognition receptors in antifungal immunity

A Plato, SE Hardison, GD Brown - Seminars in immunopathology, 2015 - Springer
Receptors of the innate immune system are the first line of defence against infection, being
able to recognise and initiate an inflammatory response to invading microorganisms. The …

[HTML][HTML] Chromoblastomycosis: an etiological, epidemiological, clinical, diagnostic, and treatment update

AC Brito, MJS Bittencourt - Anais brasileiros de dermatologia, 2018 - SciELO Brasil
Chromoblastomycosis is a chronic, granulomatous, suppurative mycosis of the skin and
subcutaneous tissue caused by traumatic inoculation of dematiaceous fungi of the family …