Unlocking the potential of antibody–drug conjugates for cancer therapy
Nine different antibody–drug conjugates (ADCs) are currently approved as cancer
treatments, with dozens more in preclinical and clinical development. The primary goal of …
treatments, with dozens more in preclinical and clinical development. The primary goal of …
Mechanisms of chemotherapy-induced peripheral neuropathy
R Zajączkowska, M Kocot-Kępska, W Leppert… - International journal of …, 2019 - mdpi.com
Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most frequent side
effects caused by antineoplastic agents, with a prevalence from 19% to over 85%. Clinically …
effects caused by antineoplastic agents, with a prevalence from 19% to over 85%. Clinically …
A systematic review of rehabilitation and exercise recommendations in oncology guidelines
NL Stout, D Santa Mina, KD Lyons… - CA: a cancer journal …, 2021 - Wiley Online Library
Guidelines promote high quality cancer care. Rehabilitation recommendations in oncology
guidelines have not been characterized and may provide insight to improve integration of …
guidelines have not been characterized and may provide insight to improve integration of …
A practical review of proteasome pharmacology
TA Thibaudeau, DM Smith, Q Ma - Pharmacological reviews, 2019 - Elsevier
The ubiquitin proteasome system (UPS) degrades individual proteins in a highly regulated
fashion and is responsible for the degradation of misfolded, damaged, or unneeded cellular …
fashion and is responsible for the degradation of misfolded, damaged, or unneeded cellular …
[HTML][HTML] Treatment and diagnosis of chemotherapy-induced peripheral neuropathy: an update
AD Desforges, CM Hebert, AL Spence, B Reid… - Biomedicine & …, 2022 - Elsevier
When peripheral neuropathy occurs due to chemotherapy treatment, it is referred to as
chemotherapy-induced peripheral neuropathy (CIPN). Typically, symptoms are sensory …
chemotherapy-induced peripheral neuropathy (CIPN). Typically, symptoms are sensory …
Cisplatin in liver cancer therapy
S Hamaya, K Oura, A Morishita, T Masaki - International Journal of …, 2023 - mdpi.com
Hepatocellular carcinoma (HCC) is the most common primary liver tumor and is often
diagnosed at an unresectable advanced stage. Systemic chemotherapy as well as …
diagnosed at an unresectable advanced stage. Systemic chemotherapy as well as …
Effects of exercise on cancer patients suffering chemotherapy-induced peripheral neuropathy undergoing treatment: a systematic review
Background Chemotherapy-induced peripheral neuropathy (CIPN) is the most common
neurological and clinically relevant side effect of many commonly used chemotherapeutic …
neurological and clinically relevant side effect of many commonly used chemotherapeutic …
Platinum‐induced peripheral neurotoxicity: from pathogenesis to treatment
NP Staff, G Cavaletti, B Islam… - Journal of the …, 2019 - Wiley Online Library
Platinum‐induced peripheral neurotoxicity (PIPN) is a common side effect of platinum‐
based chemotherapy that may cause dose reduction and discontinuation, with oxaliplatin …
based chemotherapy that may cause dose reduction and discontinuation, with oxaliplatin …
Neuropathic pain: delving into the oxidative origin and the possible implication of transient receptor potential channels
C Carrasco, M Naziroǧlu, AB Rodríguez… - Frontiers in …, 2018 - frontiersin.org
Currently, neuropathic pain is an underestimated socioeconomic health problem affecting
millions of people worldwide, which incidence may increase in the next years due to …
millions of people worldwide, which incidence may increase in the next years due to …
[PDF][PDF] Treatment of chemotherapy-induced peripheral neuropathy: systematic review and recommendations
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a commonly
encountered disease entity following chemotherapy for cancer treatment. Although only …
encountered disease entity following chemotherapy for cancer treatment. Although only …