Unlocking the potential of antibody–drug conjugates for cancer therapy

JZ Drago, S Modi, S Chandarlapaty - Nature Reviews Clinical …, 2021 - nature.com
Nine different antibody–drug conjugates (ADCs) are currently approved as cancer
treatments, with dozens more in preclinical and clinical development. The primary goal of …

Mechanisms of chemotherapy-induced peripheral neuropathy

R Zajączkowska, M Kocot-Kępska, W Leppert… - International journal of …, 2019 - mdpi.com
Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most frequent side
effects caused by antineoplastic agents, with a prevalence from 19% to over 85%. Clinically …

A systematic review of rehabilitation and exercise recommendations in oncology guidelines

NL Stout, D Santa Mina, KD Lyons… - CA: a cancer journal …, 2021 - Wiley Online Library
Guidelines promote high quality cancer care. Rehabilitation recommendations in oncology
guidelines have not been characterized and may provide insight to improve integration of …

A practical review of proteasome pharmacology

TA Thibaudeau, DM Smith, Q Ma - Pharmacological reviews, 2019 - Elsevier
The ubiquitin proteasome system (UPS) degrades individual proteins in a highly regulated
fashion and is responsible for the degradation of misfolded, damaged, or unneeded cellular …

[HTML][HTML] Treatment and diagnosis of chemotherapy-induced peripheral neuropathy: an update

AD Desforges, CM Hebert, AL Spence, B Reid… - Biomedicine & …, 2022 - Elsevier
When peripheral neuropathy occurs due to chemotherapy treatment, it is referred to as
chemotherapy-induced peripheral neuropathy (CIPN). Typically, symptoms are sensory …

Cisplatin in liver cancer therapy

S Hamaya, K Oura, A Morishita, T Masaki - International Journal of …, 2023 - mdpi.com
Hepatocellular carcinoma (HCC) is the most common primary liver tumor and is often
diagnosed at an unresectable advanced stage. Systemic chemotherapy as well as …

Effects of exercise on cancer patients suffering chemotherapy-induced peripheral neuropathy undergoing treatment: a systematic review

F Duregon, B Vendramin, V Bullo, S Gobbo… - Critical reviews in …, 2018 - Elsevier
Background Chemotherapy-induced peripheral neuropathy (CIPN) is the most common
neurological and clinically relevant side effect of many commonly used chemotherapeutic …

Platinum‐induced peripheral neurotoxicity: from pathogenesis to treatment

NP Staff, G Cavaletti, B Islam… - Journal of the …, 2019 - Wiley Online Library
Platinum‐induced peripheral neurotoxicity (PIPN) is a common side effect of platinum‐
based chemotherapy that may cause dose reduction and discontinuation, with oxaliplatin …

Neuropathic pain: delving into the oxidative origin and the possible implication of transient receptor potential channels

C Carrasco, M Naziroǧlu, AB Rodríguez… - Frontiers in …, 2018 - frontiersin.org
Currently, neuropathic pain is an underestimated socioeconomic health problem affecting
millions of people worldwide, which incidence may increase in the next years due to …

[PDF][PDF] Treatment of chemotherapy-induced peripheral neuropathy: systematic review and recommendations

S Hou, B Huh, HK Kim, KH Kim, S Abdi - Pain Physician, 2018 - painphysicianjournal.com
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a commonly
encountered disease entity following chemotherapy for cancer treatment. Although only …