Population genomics and the statistical values of race: an interdisciplinary perspective on the biological classification of human populations and implications for …

KN Maglo, TB Mersha, LJ Martin - Frontiers in Genetics, 2016 - frontiersin.org
The biological status and biomedical significance of the concept of race as applied to
humans continue to be contentious issues despite the use of advanced statistical and …

Signals transduced by Eph receptors and ephrin ligands converge on MAP kinase and AKT pathways in human cancers

A Lau, N Le, C Nguyen, RP Kandpal - Cellular Signalling, 2023 - Elsevier
Eph receptors, the largest known family of receptor tyrosine kinases, and ephrin ligands
have been implicated in a variety of human cancers. The novel bidirectional signaling …

[HTML][HTML] Relationship between West African ancestry with lung cancer risk and survival in African Americans

KA Mitchell, E Shah, ED Bowman, A Zingone… - Cancer Causes & …, 2019 - Springer
Abstract Purpose African Americans, especially men, have a higher incidence of lung cancer
compared with all other racial and ethnic groups in the US. Self-reported race is frequently …

Influence of Admixture on Phenotypes

SW Brugger, MF Davis - Current Protocols, 2023 - Wiley Online Library
Individuals of European descent have historically been the focus of genetic studies and
possess relatively homogenous genomes. As a result, analytical methods have been …

Genetic ancestry and prostate cancer susceptibility SNPs in Puerto Rican and African American men

M Irizarry‐Ramírez, RA Kittles, X Wang… - The …, 2017 - Wiley Online Library
Background The Puerto Rican (PR) population is a racially admixed population that has a
high prostate cancer (PCa) mortality rate. We hypothesized in this pilot study that West …

[HTML][HTML] Strengthening capacity for prostate cancer early diagnosis in West Africa amidst the COVID-19 pandemic: A realist approach to rethinking and …

EF Ezenwankwo, DA Nnate, CA Oladoyinbo… - Annals of Global …, 2022 - ncbi.nlm.nih.gov
Two years after SARS-CoV-2 (COVID-19) was declared a global public health emergency,
the restoration, at least, to the pre-pandemic level of early diagnostic services for prostate …

Genetic admixture and obesity: recent perspectives and future applications

JR Fernández, KE Pearson, KP Kell… - Human heredity, 2013 - karger.com
The process of the colonization of the New World that occurred centuries ago served as a
natural experiment, creating unique combinations of genetic material in newly formed …

Emerging genomic biomarkers for improving kidney, prostate, and bladder cancer health disparities outcomes

KA Mitchell, H Williams - Urologic Oncology: Seminars and Original …, 2022 - Elsevier
Background Recent advances in genomic and genetic technologies have facilitated better
health outcomes for urologic cancer patients. Genomic and genetic heterogeneity may …

Association of genetic ancestry with colorectal tumor location in Puerto Rican Latinos

J Pérez-Mayoral, M Soto-Salgado, E Shah, R Kittles… - Human Genomics, 2019 - Springer
Background Colorectal cancer (CRC) is the first cause of cancer deaths among Puerto
Ricans. The incidence and mortality of CRC in Puerto Rico continue to be on the rise. The …

Integrative multi-omics profiling of colorectal cancer from a Hispanic/Latino cohort of patients

B Waldrup, F Carranza, Y Jin, Y Amzaleg, M Postel… - medRxiv, 2024 - medrxiv.org
Colorectal cancer contributes to cancer-related deaths and health disparities in the Hispanic
and Latino community. To probe both the biological and genetic bases of the disparities, we …