Recent Updates on Interaction Studies and Drug Delivery of Antimalarials with Serum Albumin proteins

K Azeem, I Irfan, Q Rashid, S Singh… - Current Medicinal …, 2024 - ingentaconnect.com
This review focuses on recent trends in the binding study of various antimalarial agents with
serum albumins in detail. Serum albumin has a significant role in the transport of drugs and …

Exploring the interaction of hesperetin-mediated green synthesised gold and silver nanoparticles with human serum albumin: A comparative analysis

A Raj, L Vidya, TNV Vinod, S Neelima… - Journal of Molecular …, 2024 - Elsevier
This study focused on evaluating the potential of hesperetin-functionalized silver (H-AgNPs)
and gold nanoparticles (H-AuNPs) for biomedical use, with a primary objective of …

A comprehensive multispectroscopic and computational analysis of the interaction between plant-based antiplasmodial compounds and bovine serum albumin

K Azeem, HT Abdulhameed, A Hussain, S Amir… - ACS …, 2024 - ACS Publications
This study was conducted to explore the interaction between two plant-based antiplasmodial
compounds, gartanin and friedelin, and bovine serum albumin (BSA). The objectives aimed …

Evaluating Terrestrol A as an Inhibitor Against SARS‐CoV‐2and Invasive Fungal Pathogens: A Comprehensive Computational Analysis

B Singha, B Arora, R Karmaker, K Richa… - …, 2024 - Wiley Online Library
The highly contagious SARS‐CoV‐2 virus, which initiated the COVID‐19 pandemic, has
resulted in a significant loss of life worldwide. While vaccines and therapeutics have helped …

Exploring the binding mechanism and esterase-like activity of human serum albumin with levofloxacin and its choline based conjugates: A biophysical approach

AR Bhat, R Patel - International Journal of Biological Macromolecules, 2024 - Elsevier
Human serum albumin (HSA) effectively binds to compounds having different molecular
weight and thus facilitates their distribution in the living organisms. Thus, the binding …

Comparative investigation on interaction between potent antimalarials and human serum albumin using multispectroscopic and computational approaches

K Azeem, M Ahmed, A Uddin, S Singh, R Patel… - …, 2023 - Wiley Online Library
This study performed a comparative investigation to explore the interaction mechanisms
between two potential antimalarial compounds, JMI 346 and JMI 105, and human serum …

Synergistic antimicrobial activity, MD simulation studies and crystal structure of natural alcohol motif containing novel substituted cinnamates

I Irfan, A Ali, A Ubaid, Y Sherwani, B Arora… - Journal of …, 2024 - Taylor & Francis
A series of natural alcohols motif containing novel substituted cinnamates were developed
and screened against five bacterial strains namely, Enterococcus faecal (E. faecalis) …

A comprehensive investigation of the nano-[Cu2-(DIP) 2-EA] effects on HSA through spectroscopic procedures and computer simulations

N Shahabadi, L Ghaffari - Heliyon, 2024 - cell.com
In this research, the toxicity of nano-[Cu 2-(DIP) 2-EA], a metal nano-complex consisting of
ellagic acid and bathophenanthroline ligands, on human serum albumin (HSA) at a protein …

The effect of chrysin binding on the conformational dynamics and unfolding pathway of human serum albumin

I Bisaria, C Chauhan, SA Muthu, S Parvez… - Spectrochimica Acta Part …, 2024 - Elsevier
Studies on the interactions between ligands and proteins provide insights into how a
possible medication alters the structures and activities of the target or carrier proteins. The …

[HTML][HTML] Electronic and vibrational spectroscopic study complemented with the computational evaluation of hydroxychloroquine mixed with silver nanoparticles

NM Mwenze, Z Birech, M Juma, R Morad, KJ Cloete… - Results in …, 2024 - Elsevier
Synthesized silver nanoparticles via laser liquid ablation were characterized using XRD,
TEM, EDS, UV–Vis, and Raman spectroscopy. The AgNPs were then conjugated with HCQ …